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Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle (Paperback, Softcover reprint of the original 1st ed. 1992)
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Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle (Paperback, Softcover reprint of the original 1st ed. 1992)
Series: Advances in Experimental Medicine and Biology, 311
Expected to ship within 10 - 15 working days
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The Third International Symposium on Excitation-Contraction
Coupling in Skeletal, Cardiac, and Smooth Muscle, organized by
George Frank, C. Paul Bianchi, and Henk E. DJ. ter Keurs, was held
in Banff Centre, Banff, Alberta, Canada during June 26 to June 30,
1991. The theme of these symposia has been to recognize the
similarities and dissimilarities of excitation-contraction coupling
in skeletal, cardiac, and smooth muscle. Cross fertilization of
concepts of excitation-contraction coupling in these three types of
muscle has occurred since the early studies in the late fifties and
early sixties on skeletal muscle. Investigators in each field meet
only at specialized symposia which exclude investigators in the
other fields. The purpose of the symposia has been to bring
together international investigators studying
excitation-contraction coupling in skeletal, cardiac, and smooth
muscle so that we may learn from each other and hence provide a
more global concept of excitation-contraction. The Third
International Symposia has accomplished its objective as we
recognize that calcium channels of the sarcolemma and the
sarcoplasmic reticulum play key essential roles in
excitation-contraction coupling in all three types of muscles. In
skeletal muscle the recognition that E-C coupling consists of two
parallel mechanisms, one dependent upon a dihydropyridine
voltage-sensitive sensors coupled to calcium release from the
terminal cisternae via the ryanodine sensitive channel in the foot
structure of the triad.
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