Although various analytical techniques are available for the
evaluation of drugs, chromatographic analysis are considered better
due to the their stability, reproducibility and sensitivity. In
recent years, the development of HPLC methods for the determination
of drugs has attracted considerable attention of
pharmacokineticians due to their importance in the quality control
tests of drugs and their formulations. A world wide competition is
in progress for developing rapid, convenient and sensitive HPLC
methods in quality control testing. This book provides basic
guidelines for the HPLC calibration, and method development for the
rapid quantification of cetrizine. This method was validated and
applied for the determination of cetrizine in tablets and their
stability studies. This book is useful to the pharmacokineticians
who are interested in the development and validation of stability
indicating HPLC methods for cetrizine HCl and other drugs of same
physico-chemical properties.
General
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