Stroke is a leading cause of death in developed countries. However,
current therapeutic strategies for stroke have been largely
unsuccessful. One possible explanation is that research and
pharmacological management have focused on very early events in
brain ischemia. New research has shown that brain ischemia and
trauma elicit strong inflammatory reactions driven by both external
and brain cells. The recognition of inflammation as a fundamental
response to brain ischemia provides novel opportunities for new
anti-inflammatory therapies. For the first time, an international
body of researchers presents the latest findings about the cellular
and humoral aspects of immune and inflammatory reactions in the
brain. The work may have an impact on the treatment of
neuroinjuries and ancillary brain diseases, and increase the
understanding of the roles infections and immune reactions play in
the brain milieu.
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