This book summarizes the state-of-the-art knowledge on naturally
occurring organohalogens, of which more than 3700 are documented.
The chapters cover all aspects of this field, including the
structural diversity and sources of organohalogens, the mechanisms
for their formation and biodegradation, the clinical use of
dichloroacetate, and the synthesis of the powerful anticancer
chlorine-containing cryptophycin. Both biogenic and abiogenic
sources of organohalogens are treated, the latter of which include
volcanic emissions and abiogenic formation in soil. Halogenation in
humans, fungi, and in the ocean are covered in separate chapters.
Sources and biosynthesis of the relatively rare natural
organofluorines are also discussed in this volume. By better
understanding of the role nature plays in the area of
organohalogens, we can more intelligently regulate the production,
use, and disposal of man-made organohalogen compounds.
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