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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Rab GTPases - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2015)
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Rab GTPases - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2015)
Series: Methods in Molecular Biology, 1298
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This volume covers the latest technological advances in the
characterization of the biosynthesis and functions of Rab GTPases
and their regulation by guanine nucleotide exchange factors (GEFs)
and GTPase-activating proteins (GAPs). The book consists of 28
chapters and starts with an overview of the Rab GTPase family. The
next few chapters describe systematic approaches to the
identification and classification of Rabs and Rab GAPs, as well as
the detection of Rab isoprenylation and membrane distribution. The
last few chapters examine the biochemical and functional properties
of individual Rabs in the order of exocytic, recycling and
endocytic Rabs. Written in the highly successful Methods of
Molecular Biology series format, chapters include introductions to
their respective topics, lists of the necessary materials and
reagents, step-by-step, readily reproducible laboratory protocols
and key tips on troubleshooting and avoiding known pitfalls.
Instructive and practical, Rab GTPases: Methods and Protocols
approaches each topic with great detail and is a valuable resource
for researchers and students interested in the field of Rab
GTPases.
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