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Histone Variants - Methods and Protocols (Hardcover, 1st ed. 2018)
Loot Price: R5,602
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Histone Variants - Methods and Protocols (Hardcover, 1st ed. 2018)
Series: Methods in Molecular Biology, 1832
Expected to ship within 12 - 17 working days
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This volume compiles methodologies used for detailed studies of
histone variants, from their basic properties to their functional
roles in chromatin and as vectors of epigenetic information. Its
four sections cover experimental approaches to probe the
biochemistry of histone variants and variant nucleosomes; their
dynamics throughout the cell cycle and at specific genomic
locations; their functional impact on chromosome organization and
genome stability; and their importance in development, disease and
evolution. Written in the highly successful Methods in Molecular
Biology series format, chapters include lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, illustrations on the expected results, and
tips on troubleshooting and avoiding known pitfalls. This anthology
brings together contributions from many of the most highly
recognized investigators in this community. Cutting-edge and
thorough, Histone Variants: Methods and Protocols is a valuable
resource for anyone interested in exploring the experimental and
collaborative possibilities in this evolving field.
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