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Kinomics - Approaches and Applications (Hardcover)
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Kinomics - Approaches and Applications (Hardcover)
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Authored by the world's leading kinase experts, this is a
comprehensive introduction to current knowledge and practice within
this emerging field. Following an overview of the major players and
pathways that define the kinome, the major part of this work is
devoted to current strategies of kinome investigation and
manipulation. As such, kinase engineering, peptide substrate
engineering, co-substrate design and kinase inhibitor design are
discussed in detail, and their potential applications in kinome
analysis and kinome-based pharmacotherapy are shown. The result is
a toolbox for every kinase researcher: By addressing and comparing
current approaches to the study of kinase action, both novice and
established researchers will benefit from the practical knowledge
contained in this invaluable reference.
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