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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Clinical Cardiogenetics (Paperback, 2011 ed.)
Loot Price: R4,423
Discovery Miles 44 230
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Clinical Cardiogenetics (Paperback, 2011 ed.)
Expected to ship within 10 - 15 working days
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Clinical management and signs are the focus of this practical
cardiogenetic reference for those who are involved in the care for
cardiac patients with a genetic disease. With detailed discussion
of the basic science of cardiogenetics in order to assist in the
clinical understanding of the topic. The genetic causes of various
cardiovascular diseases are explained in a concise clinical way
that reinforces the current management doctrine in a practical
manner. The authors will cover the principles of molecular genetics
in general but also specific to cardiac diseases. They will discuss
the etiology, pathogenesis, pathophysiology, clinical presentation,
clinical diagnosis, molecular diagnosis and treatment of each
cardiogenetic disease separately. Therapy advice, ICD indications,
indications for and manner of further family investigation will all
be covered, while each chapter will also contain take-home messages
to reinforce the key points. The chapters reviewing the different
diseases will each contain a table describing the genes involved in
each. Each chapter will also contain specific illustrations,
cumulatively giving a complete, practical review of each
cardiogenetic disease separately. Special emphasis will be given to
advice on how to diagnose and manage cardiogenetic diseases in
clinical practice, which genes should be investigated and why, and
the pros and cons of genetic testing. Guidelines for investigation
in families with sudden cardiac death at young age will also be
included. This book will be written for the general cardiologist
and the clinical geneticist who is involved in cardiac patients and
will provide answers to question such as: Which genes are involved
and which mutations? What is the effect of the mutation at cellular
level? Which genes should be tested and why? What is the value of a
molecular diagnosis? Does it influence therapy? When should the
first degree relatives be tested and in which way?
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