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Oxidative Stress and Signal Transduction (Hardcover, 1997 ed.)
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Oxidative Stress and Signal Transduction (Hardcover, 1997 ed.)
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In the past few years there has been the increased recognition that
the effects of oxidative stress are not limited to the damage of
cellular constituents. There is now evidence that reactive oxygen
species (ROS) can alter cell function by acting upon the
intermediates, or second messengers, in signal transductions. Such
effects on signaling mechanisms probably account for the role of
oxidative stress in inflammation, aging, and cancer. This volume
brings together internationally recognized researchers in both the
major areas covered by the book, oxidative stress and signal
transduction. The work is organized in three sections. The first
deals with the immediate cellular responses to oxidative stress and
the production of second messengers. The second details the
connection between second messengers and the gene. The third part
looks more closely at the level of the gene.
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