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Bioinformatics and Genome Analysis (Paperback, Softcover reprint of the original 1st ed. 2002)
Loot Price: R2,782
Discovery Miles 27 820
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Bioinformatics and Genome Analysis (Paperback, Softcover reprint of the original 1st ed. 2002)
Series: Ernst Schering Foundation Symposium Proceedings, 38
Expected to ship within 10 - 15 working days
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Total price: R2,802
Discovery Miles: 28 020
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Bioinformatics is emerging as a field with ever-increasing promise,
ur- gency, and necessity. All three of these facets can be seen in
the con- text of the recent sequencing of the human genome. The
creation of a novel algorithm for the assembly of whole genome
shotgun data sets accelerated the project and resulted in its near
completion in 2001. The urgency became apparent with the landslide
of data that ensued and the realization that current databases and
tool sets are not up to the task. Finally, the necessity of
bioinformatics as a facet of molecular biologi- cal research
becomes evident in the impossibility of individual human
comprehension of all the details of the functioning of a cell at
the mo- lecular level, especially now that we stand on the edge of
this preci- pice. We find ourselves at a time when we have the
essentially complete genomes of human and mouse, and the completed
sequences of Droso- phila melanogaster, Caenorhabditis elegans,
several fungi including Saccharomyces cerevisiae, and many bacteria
including Escherichia coli. There are volumes of mRNA expression
data sets, high-density maps of highly variable SNPs for both human
and mouse, physical marker maps for many other important
agricultural and drug trial ani- mals, and a complete knock-out
survey of yeast. In addition, the se- quencing of D. pseudoobscura
and Caenorhabditis briggsae in the near future will provide unusual
comparative genomic insights.
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