Applications of Novel Substituted Biphenyl-Sulfonamides (Paperback)

The objectives of this work is comparing three different kinds of sulfonamide compounds by evaluating structure modification through their examination towards more important properties such as: (a) Surface properties of the synthesized sulfonamide compounds were studied through surface parameters cmc, (cmc), A(min) and (max). Most of these tested compounds have remarkable surface activity. (b) The target compounds were tested to determine structure-biological activity relationship against different types of pathogenic bacterial species. The amine acid salts of bis (2-aminophenyl) biphenyl-4,4'-disulfonamide (Series B) were the powerfully effective series. Only carboxylic acid salts of bis (2-aminophenyl)biphenyl-4,4'- disulfonamide (Series B) were powerfully effective series against selected pathogenic fungal species. (c) Selected compounds were screened for cytotoxicity against selected human tumor cell lines - MCF7, HEPG2, and HCT116. Most of tested compounds have potent cytotoxic activity against liver carcinoma and colon carcinoma, meanwhile, exhibit moderate activity against breast carcinoma."

General

Imprint:	Lap Lambert Academic Publishing
Country of origin:	Germany
Release date:	August 2010
First published:	August 2010
Authors:	Hanan Ahmed • Abdelfattah Badawi • Ahmed Fify
Dimensions:	229 x 152 x 6mm (L x W x T)
Format:	Paperback - Trade
Pages:	100
ISBN-13:	978-3-8383-8739-0
Categories:	Books > Professional & Technical > Biochemical engineering > General Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Chemical engineering
LSN:	3-8383-8739-2
Barcode:	9783838387390

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