Myeloid Leukemia - Methods and Protocols (Hardcover, 2006 ed.)

A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies. Highlights include techniques for the detection of BCR-ABL mutations and resistance to imatinib mesylate, detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia, classification of AML by DNA-oligonucleotide microarrays, and detection of the V617F JAK2 mutation in myeloproliferative disorders. In addition to gene rearrangments, other prognostically relevant molecular lesions such as FLT3 mutations and WT-1 overexpression are covered.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Medicine, 125
Release date:	November 2005
First published:	2006
Editors:	Harry Iland • Mark Hertzberg • Paula Marlton
Dimensions:	235 x 155 x 27mm (L x W x T)
Format:	Hardcover
Pages:	307
Edition:	2006 ed.
ISBN-13:	978-1-58829-485-2
Categories:	Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-58829-485-4
Barcode:	9781588294852

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