Selective decontamination is a technique which combines short-term
and long-term antimicrobials to prevent or treat the acquisition
and subsequent carriage of microorganisms causing late colonization
and infections. The antimicrobials are selective in that they leave
the indigenous, mostly anaerobic flora more or less intact, whilst
the effective decontamination provides a genuine breakthrough in
the endogenous route of pathogenesis. The improvements in
decontamination techniques presented here offer significant
reduction in infection related morbidity and mortality among trauma
patients.
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