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3D QSAR in Drug Design - Recent Advances (Hardcover, Volume 2 also available as Volumes 9-11 (1997) and Volume 3 as Volumes 12-14 (1998) of PERSPECTIVES IN DRUG DISCOVERY AND DESIGN, 1998)
Loot Price: R5,634
Discovery Miles 56 340
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3D QSAR in Drug Design - Recent Advances (Hardcover, Volume 2 also available as Volumes 9-11 (1997) and Volume 3 as Volumes 12-14 (1998) of PERSPECTIVES IN DRUG DISCOVERY AND DESIGN, 1998)
Series: Three-Dimensional Quantitative Structure Activity Relationships, 3
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Significant progress has been made in the study of
three-dimensional quantitative structure-activity relationships (3D
QSAR) since the first publication by Richard Cramer in 1988 and the
first volume in the series, 3D QSAR in Drug Design. Theory, Methods
and Applications, published in 1993. The aim of that early book was
to contribute to the understanding and the further application of
CoMFA and related approaches and to facilitate the appropriate use
of these methods. Since then, hundreds of papers have appeared
using the quickly developing techniques of both 3D QSAR and
computational sciences to study a broad variety of biological
problems. Again the editor(s) felt that the time had come to
solicit reviews on published and new viewpoints to document the
state of the art of 3D QSAR in its broadest definition and to
provide visions of where new techniques will emerge or new appli-
tions may be found. The intention is not only to highlight new
ideas but also to show the shortcomings, inaccuracies, and abuses
of the methods. We hope this book will enable others to separate
trivial from visionary approaches and me-too methodology from in-
vative techniques. These concerns guided our choice of
contributors. To our delight, our call for papers elicited a great
many manuscripts.
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