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Transmembrane Signaling Protocols (Hardcover, 2nd ed. 2006)
Loot Price: R3,200
Discovery Miles 32 000
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Transmembrane Signaling Protocols (Hardcover, 2nd ed. 2006)
Series: Methods in Molecular Biology, 332
Expected to ship within 12 - 17 working days
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Total price: R3,220
Discovery Miles: 32 200
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The previous edition of Transmembrane Signaling Protocols was
published in 1998. Since then the human genome has been completely
sequenced and new methods have been developed for the use of
microarrays and proteomics to analyze global changes in gene
expression and protein profiles. These advances have increased our
ability to understand transmembrane signaling processes in much
greater detail. They have also simultaneously enhanced our ability
to determine the role of a large number of newly identified
molecules in signaling events. In addition, novel video microscopy
methods have been developed to image transmembrane signaling events
in live cells in real time. In view of these major advances, it is
time to update the previous edition. Because of the success of that
volume, we have chosen to keep the essential character of the book
intact. Introductory chapters from experts have been included to
provide overall perspective and an overview of recent advances in
signal transduction pathways. The individual chapters now include
comp- hensive detailed methods, studies in genetically tractable
systems, fluorescence microscopy in live single cells, ex vivo
analysis of primary cells from tra- genic mice, as well as genomic
and proteomic approaches to the analysis of transmembrane signaling
events. We would like to express our deep gratitude to the
coauthors of this publi- tion. We hope that Transmembrane Signaling
Protocols, Second Edition will serve as a valuable resource for
future progress in the study of signal transd- tion pathways.
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