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Books > Medicine > Clinical & internal medicine > Paediatric medicine
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Fundamentals of Pediatric Drug Dosing (Hardcover, 1st ed. 2016)
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Fundamentals of Pediatric Drug Dosing (Hardcover, 1st ed. 2016)
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Focused on pediatric physiology, pharmacology, pharmacokinetics and
pharmacodynamics, this book illustrates the differences between the
pediatric population and adults; knowledge of extreme importance
not only during pediatric drug development but also in the clinical
practice. Physicians, nurses, clinical pharmacologists, researchers
and healthcare professionals will find this an invaluable resource.
With the advent of pediatric exclusivity, and requirements to
conduct clinical studies in children, an emphasis has been placed
on finding a safe and efficacious dose of a drug in children.
Children are not 'small adults', and drug dosing in this population
requires special consideration. There are subtle physiological and
biochemical differences among neonates, infants, children,
adolescents and adults and dosing in pediatrics requires proper
understanding of these factors. Furthermore, dosing in children, as
in adults, should be based on pharmacokinetic and pharmacodynamic
data. This is an evolving area, as pediatric pharmacokinetic
studies are becoming mandatory for getting approval of new drugs in
this population.
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