|
Books > Science & Mathematics > Biology, life sciences > Biochemistry
|
Buy Now
Glycobiology Protocols (Hardcover, 2007 ed.)
Loot Price: R4,408
Discovery Miles 44 080
|
|
|
Glycobiology Protocols (Hardcover, 2007 ed.)
Series: Methods in Molecular Biology, 347
Expected to ship within 10 - 15 working days
|
Glycobiology involves studies of complex carbohydrates and
posttrans- tional modifications of proteins, and has become an
important interdiscip- nary field encompassing chemistry,
biochemistry, biology, physiology, and pathology. Although initial
research was directed toward elucidation of the different
carbohydrate structures and the enzymes synthesizing them, the
field has now moved toward identifying the functions of
carbohydrates. The pro- cols described in Glycobiology Protocols
form a solid basis for investigations of glycan functions in health
and disease. The cloning of many of the genes participating in
glycosylation processes has helped to enhance our knowledge of how
glycosylation is controlled, but has also added another dimension
of complexity to the great heterogeneous variety of the structures
of the oligos- charides of glycoproteins, proteoglycans, and
glycolipids. A family of similar enzyme proteins exists for each
glycosylation step. Glycosyltransferases are extremely specific for
both the nucleotide sugar donor and the acceptor s- strate, but
many other factors control sugar transfer, including the locali-
tion and topology of enzymes, cofactors, possible chaperone
proteins, and the availability of sugar acceptor substrates. The
analysis of the intracellular organization of glycosylation and of
the factors controlling the activities of the participating enzymes
in the cell are important areas that need more research efforts.
Another challenge for future research is to understand the
glycodynamics of a cell, that is, how the cell responds to stimuli
leading to biological and pathological changes in terms of
alterations in glycosylation, and how this affects the biology of
the cell.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
You might also like..
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
