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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > Allergies
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Mouse Models of Allergic Disease - Methods and Protocols (Hardcover, 2013 ed.)
Loot Price: R3,100
Discovery Miles 31 000
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Mouse Models of Allergic Disease - Methods and Protocols (Hardcover, 2013 ed.)
Series: Methods in Molecular Biology, 1032
Expected to ship within 10 - 15 working days
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Over the last half century, a dramatic increase in allergic
diseases has been observed throughout industrialized nations, which
has resulted in significant worldwide socio-economic challenges. In
Mouse Models of Allergic Disease: Methods and Protocols, a wide
range of expert contributors provide detailed protocols for the
design and execution of experiments to thoroughly analyze critical
elements associated with a diverse range of allergic diseases, all
through the lens of mouse models that accurately recapitulate
clinically relevant aspects of the respective human disease. The
volume opens with a section featuring techniques essential for
effective ex vivo cell isolation and evaluation of specific cell
types relevant to a diverse range of allergic diseases, and the
book then moves on to cover in vivo protocols to evaluate prevalent
mouse models of human allergic diseases, including mouse models of
systemic anaphylaxis, contact hypersensitivity, allergic rhinitis,
and asthma, as well as a collection of chapters on in vivo and ex
vivo protocols used to assess indirect mediators of allergic
diseases, such as the nervous system, non-hematopoietic cells, and
the composition of the gut microbiome. Written in the highly
successful Methods in Molecular Biology series, chapters include
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and tips on troubleshooting and avoiding
known pitfalls. Timely and authoritative, Mouse Models of Allergic
Disease: Methods and Protocols serves as an essential collection of
protocols that allow both novice and expert researchers the ability
to accurately develop, evaluate, and characterize the mechanisms
associated with these disorders.
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