The scope of this book includes several contro apparent instability
of viewpoint and nomenclature versial areas and it is impossible to
give an account has made many wary. but it is hoped that an under
which satisfies everyone. including the author. lying simple basis
will allow future changes to be However. the prime objective has
been to aid in the easily assimilated. interpretation of
histopathological appearances in Detailed accounts of methods of
classification lymph nodes. To that end. there is some attempt at
are omitted. being widely available elsewhere. nor rationalization
whilst admitting that. in rationalizing is there any attempt to be
comprehensive. The biological processes. there is a danger of
distortion discussion is limited almost exclusively to the and
inconsistency. appearances in routine sections. stained with haema
Normal structure and function of lymph nodes is toxylin and eosin.
with the addition of a few special taken as the backbone from which
reactive changes stains. since additional technical methods are not
on the one hand. and neoplastic transformation on always available.
The limitations that this imposes the other. can be seen to take
their origin. Where the are acknowledged. backbone itself is
faulty. then there occur distur bances of immunological function.
which engender another group of histological changes. Lastly.
Acknowledgements essentially systemic disorders may be reflected in
I should like to thank: lymph nodes. Mrs Mary Wright who typed the
manuscript; the This simple approach can be used to bring order
Technical Staff of the Histology Laboratory."
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