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Prostaglandins, Leukotrienes, and Lipoxins - Biochemistry, Mechanism of Action, and Clinical Applications (Paperback, Softcover reprint of the original 1st ed. 1985)
Loot Price: R1,585
Discovery Miles 15 850
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Prostaglandins, Leukotrienes, and Lipoxins - Biochemistry, Mechanism of Action, and Clinical Applications (Paperback, Softcover reprint of the original 1st ed. 1985)
Series: Gwumc Department of Biochemistry and Molecular Biology Annual Spring Symposia
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Total price: R1,605
Discovery Miles: 16 050
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The family of known essential fatty acid metabolites continues to
grow. Synthesis of the prostaglandins from essential fatty acids
was first described by Bergstrom and Samuelsson in 1964. The
thromboxanes were discovered in 1975, the pros- tacyclins, by
Moncada and Vane, in 1976, and the leukotrienes by Samuelsson in
1979. The discovery of a new class of biologically active
arachidonic acid metab- olites named lipoxins was announced by
Bengt Samuelsson at the IVth International Spring Symposium on
Health Sciences held in Washington D. C. , May 1984. This volume,
Prostaglandins, Leukotrienes and Lipoxins, contains most of the
papers presented in the plenary sessions of the Washington
Symposium. The book is divided into six parts, each covering a
different aspect of this rapidly expanding field, and contains a
total of 63 chapters by an internationally recognized group of
authors in each area. Part I contains 11 chapters and covers the
basic biochemistry and enzymology of prostaglandins, leukotrienes,
and lipoxins. Chapter 1 by Professor Samuelsson details the
discovery of lipoxins. The enzymatic synthesis and biological
activities of the first two members of this series, lipoxins A and
B, are described. They appear to have selective secretagogue
activity for human neutrophils. The lipoxins contain a conjugated
trihydroxytetraene structure and thus differ significantly from the
previously described leukotrienes and THETEs and, in contrast to
these sub- stances, are derived by the integrated activity of two
different lipoxygenase path- ways.
General
Imprint: |
Springer-Verlag New York
|
Country of origin: |
United States |
Series: |
Gwumc Department of Biochemistry and Molecular Biology Annual Spring Symposia |
Release date: |
August 2012 |
First published: |
August 2012 |
Editors: |
J Bailey
|
Dimensions: |
229 x 152 x 36mm (L x W x T) |
Format: |
Paperback
|
Pages: |
705 |
Edition: |
Softcover reprint of the original 1st ed. 1985 |
ISBN-13: |
978-1-4684-4948-8 |
Categories: |
Books >
Science & Mathematics >
Biology, life sciences >
Biochemistry >
General
|
LSN: |
1-4684-4948-6 |
Barcode: |
9781468449488 |
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