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Books > Medicine > Clinical & internal medicine > Hepatology
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Gastric Inhibitory Polypeptide (Paperback, Softcover reprint of the original 1st ed. 1982)
Loot Price: R2,607
Discovery Miles 26 070
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Gastric Inhibitory Polypeptide (Paperback, Softcover reprint of the original 1st ed. 1982)
Series: Monographs on Endocrinology, 24
Expected to ship within 18 - 22 working days
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Dr. Raymond Pederson, Dr. Jill Dryburgh and I commenced work on GIP
in 1968, when, with the generous help of Professor Viktor Mutt and
Professor Erik Jorpes of the Karolinska Inst, itute, Stockholm, we
were able to establish that there existed an inhibitory material
for acid secretion in cholecystokinin-pancreozymin prepara tions.
Once the physiological evidence for the inhibitor was established
it seemed appropriate to seek help in its isolation. Dr. J.
Dryburgh and Dr. R. Pederson were left to bioassay fractions in
Vancouver whilst I enjoyed the company of Professor Mutt at the
Karolinska for one year, as a Medical Research Council of Canada
Visiting Scientist. Purification of the inhibitory factor proceeded
rapidly due, in no small measure, to Professor Mutt's untirmg
efforts on my behalf. Later that year, Dr. Dryburgh joined us in
Stockholm to begin the sequence work on GIP. This was completed
late in 1970 in Vancouver. In Stockholm in June 1970, I met a
fellow Canadian Dr. John Dupre (McGill University) at a cocktail
party who kept commenting about the possibility of GIP being an
insulinotropic hormone, the "incretin" of earlier days. At that
time, gastrointestinal physiologist as I was, I did not recognize
the importance of his comment. This became apparent two or three
years later when Dr. Dupre demonstrated that GIP was insulinotropic
in man. In 1972, Maryanne Kuzio and Dr."
General
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