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First International Congress on Cataract Surgery Florence, 1978 (Paperback, Softcover reprint of the original 1st ed. 1979)
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First International Congress on Cataract Surgery Florence, 1978 (Paperback, Softcover reprint of the original 1st ed. 1979)
Series: Documenta Ophthalmologica Proceedings Series, 21
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Numerous drugs administered either generally or locally have shown
a cata- ractogenic action. From a pathogenic point of view a
di,stinction must be made between drugs which modify the
transparency of the lens due to accumulation (mer- curic,'silver,
gold salts, etc.) from those influencing its metabolism. Among the
latter, Triparanol, antimitotic drugs, various phenothiazinic
derivates, corticosteroids and certain miotics cause the most
significatn dam- age. It is necessary to indicate the most frequent
reports which evidence a relationship between a prolonged
oestroprogestinic therapy and alterations of the lens transparency.
The authors also indicate pathogenic mechanisms which probably
cause iatrogenic cataracts. REFERENCES Apponi G., Rinaldi E. &
De Simone S. Cataratta monolaterale dopo iniezione endo- carotidea
di 2-3-5 Trisetilenimmino 1-4 benzochinone (Trenimon Bayer). Ann.
Ot- tal. 90, 224, 1964. Baron J.B., Morel P., Rivollan Y. &
Soulairac A.: Incidences ophtalmologiques du traitement prolonge
par la chloropromazine associee ou non Ii des troubles cutanes.
Agressiologie, 9, (2) 293, 1968. Bryk E.: Generalized argyrosis
with involvement oflenses. Klin. Oczna 26,217,1956. Conel E.B.
& Kelman C.D.: Ophthalmologic findings with oral
contraceptives. Obstet. Gynec. 31,456, 1968. Conklin, Upton &
Christenberry & MC.Donald: Citato da Duke-Elder. Radiat. Res.
19, 156,1963. Davidson S.I.: Reported adversa effects of oral
contraceptives on the eye. Trans. Oph- thai. Soc. U.K. 91,561,1971.
De Long S.L.: Incidence and significance of chloropromazine-induced
eye changes. Dis. Nerv. Syst. 29 (3), Suppl. 19, 1968.
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