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Membrane Receptors and Enzymes as Targets of Insecticidal Action (Paperback, Softcover reprint of the original 1st ed. 1986)
Loot Price: R1,518
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Membrane Receptors and Enzymes as Targets of Insecticidal Action (Paperback, Softcover reprint of the original 1st ed. 1986)
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One of the fundamental concepts of toxicology is that chemicals act
at selective receptors and that such interactions result in phar
macologic responses which, depending on dose, mayor may not result
in toxicity. For us to understand how insecticides produce their
toxic effects, we must first understand their molecular
interactions with their target receptors. With this in mind, we
organized a symposium which was given in conjunction with the XVII
International Congress of Entomology in Hamburg on August 21, 1984.
The goal of this symposium was to bring together researchers with a
wide range of expertise who shared a common interest in the action
of insecticides on the insect nervous system. It was decided to
restrict the scope of the symposium so that selected topics could
be discussed in greater depth. The volume which resulted from this
symposium, -Membranes Receptors and Enzymes as Targets of
Insecticidal Action-, details a number of bio chemical modes of
action of insecticides on the insect nervous system. The volume is
divided into two sections; the first dealing with the action of
insecticides on the GABA-ch1oride channel complex. This section
evolves from a discussion of the symptoms of cyclodiene toxicity
presented by Dr. D. E. Woolley, to the structure-activity
relationships and pharmacology of the channel complex and is
concluded with the extremely interesting work of Dr. C. C. Wang on
the action(s) of avermectin at this receptor.
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