For twenty years this book, now in its 5th edition, has provided
information on adverse drug interactions that is unrivalled in
coverage and scholarship.
Adverse drug reactions, many of them ascribable to interactions
with other drugs or with chemical substances in food or the
environment, are thought to cause or complicate one in twenty of
hospital admissions.
The book is conveniently divided into two parts: Part 1 comments
on drug interactions and their mechanisms, on a pharmacokinetic and
pharmacodynamic level, while Part 2 consists of drug interaction
tables, divided and subdivided into categories of disorders, and
the drugs used in the treatment of these disorders.
If safety in drugs is to improve, education of prescribers is
vitally important. This book, with its up-to-date and coordinated
approach, serves that purpose well. The real threat, as the authors
remind us, is the ignorance of practitioners, not the drug itself.
The volume is therefore an essential addition to the shelves of
those responsible for the prescription of drugs, in order to
prevent a potential backlash when used in combination with other
drugs or chemical substances.
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