Entry Inhibitors in HIV Therapy details the current status of
this relatively new and very dynamic class of inhibitors, appealing
to both the clinician and basic research scientist. A unique
overview of obstacles and accomplishments is presented. The book
features chapters that explain the challenges of high sequence
diversity in the viral envelope gene for the development and use of
entry inhibitors, the clinical utility of virus phenotyping, the
development of this class of inhibitors as microbicidal therapy,
and the success story of enfuvirtide from the bench to FDA
approval. Both basic research findings and results of clinical
studies are covered and linked together by a diverse panel of
experts in the field.
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