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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > HIV / AIDS
South African born-and-raised Hollywood screenwriter Helena Kriel is researching the ancient text of the Kama Sutra for a movie she’s writing. At the same time, she is travelling to India to meet with sages and find answers to the universal challenges of sex and love. While searching for love in her doomed relationships, little does she know she will find her answers in caring for her dying brother, Evan, in South Africa. Set in the mid-1990s, South Africa is just emerging from the darkness of apartheid and bursting with vibrant chaos. The story zooms in on an intense year in the narrator’s life. It centres around the lively and eccentric South African Kriel family: Maya, the combative but inspired mother; Lexi, the sister recently returned from living in a temple in India; Ross, the younger brother diving with sharks; and Helena, the narrator, herself on a journey to understand love and death. At the heart of the story is Evan, her terminally ill 30-year-old gay brother, who has been keeping his illness a shameful secret. Conscious, sensitive, terrified and trying to hang onto sanity as his world changes, Evan becomes paralysed then finally goes blind as death draws ever closer. But it is Evan who leads the family through the fire. In living through her brother’s fight to stay alive, the narrator finds herself at the heart of a savage story, one she would not have chosen. How could she know when she set out to India to find ancient solutions to the modern problems of our age that her brother’s approaching death would be her greatest teacher? How could she imagine that dying brings everything to life? The Year Of Facing Fire is an astoundingly written memoir by one of South Africa’s finest writers. It traverses universal themes including love, death and sex, and finds value in the ordinary and great beauty in the uncertain.
Since the first edition of HIV and AIDS Education, Care and Counselling was published almost 20 years ago, it has become the standard handbook in Africa for thousands of HIV and AIDS practitioners. However, ongoing HIV and AIDS research requires regular revisions to the handbook for it to remain current with developments in prevention and treatment. Consequently, this new edition has been updated with input from two new specialist co-authors. This has strengthened the multicultural and multidisciplinary approach of this edition to Africa's unique challenges.
Four decades after And the Band Played On created an image of the AIDS epidemic that has survived in the public consciousness to this very day, mathematician Rebecca Culshaw is now sounding the alarm that everything that iconic book told us about AIDS is demonstrably wrong. And that mistaken understanding of AIDS and its cause has the potential to affect all of us, not just certain so-called risk groups. In The Real AIDS Epidemic, Rebecca Culshaw describes her slow uncovering of these reasons over her years researching HIV for her work constructing mathematical models of its interaction with the immune system. It is rare that a researcher who has received funding to study HIV ever expresses any doubt in the paradigm, and an even rarer event still when she abandons the field altogether. Culshaw's book is one of the great insider-turned-whistleblower stories of our time. The Real AIDS Epidemic focuses on the politics of the changing definition of AIDS and the flaws in all HIV testing. In a much broader sense, it explains how the current, government-based structure of scientific research has corrupted science as the search for truth. It offers not only scientific reasons for HIV/AIDS being untenable, but also sociological explanations as to how the theory was accepted by the media and the world so quickly. In particular, this book offers a scathing criticism of the outrageous discriminatory measures that have been leveled at HIV-positives from the inception. She also warns that the toxic drugs being foisted on the Black and gay communities constitute one of the worst medical violations of human rights since the Tuskegee Syphilis Experiment. The compelling case she makes that the AIDS establishment has led us into a biomedical disaster through incompetence, fraud, and deceit will have many readers throwing their hands up and feeling helpless and hopeless. But she does something no other book that is critical about HIV and AIDS has done. She suggests a series of strategic actions the scientific community, Congress, the media, and the public can take to undo the damage that the powerful AIDS establishment has done since the epidemic began in 1981.
A practical guide for primary health care personnel in the clinical and supportive care of people with HIV/AIDS. This book is a user-friendly, practical guide for medical personnel who treat, care for, or support people with HIV/AIDS at the primary care level. This updated edition addresses many areas including TB, STDs, HIV testing, counselling, treatment, education terminal care, specific needs of women and children, mother to child transmission and risk and injury to health care personnel. Illustrations are used throughout the book to promote a caring, accepting attidue to AIDS. In addition to doctors and primary care nurses, this book is also useful for counsellors, social workers, psychologists, alternative health care professionals and therapists. It also serves as a useful reference guide in clinics and in the training of personnel.
'Farber [is] a lucid and courageous witness to the power-play behind the first "scamdemic," . . . [Her] work is journalism at its best—solid, lucid, and humane, attacking wrongs that few dare touch, and thereby helping right them.' —Mark Crispin Miller, bestselling author and professor of media studies at NYU On April 23, 1984, in a packed press conference room in Washington, DC, the secretary of health and human services declared, 'The probable cause of AIDS has been found.' By the next day, 'probable' had fallen away, and the novel retrovirus later named HIV became forever lodged in global consciousness as 'the AIDS virus.' Celia Farber, then an intrepid young reporter for SPIN magazine, was the only journalist to question the official narrative and dig into the science of AIDS. She reported on the 'evidence' that was being continually cited and repeated by health officials and the press, the deadliness of AZT, and Dr. Fauci’s trials on children, infants, and pregnant mothers. Throughout, Faber’s reportage was largely ignored. She was maligned, maliciously attacked, and ultimately cancelled. Now, forty years after her original reporting, Farber’s Serious Adverse Events: An Uncensored History of AIDS is reissued with a new foreword by Mark Crispin Miller, shining much-needed light on her groundbreaking work once again. More relevant than ever, this book serves as an essential foundation to understanding its catastrophic sequel: COVID-19. Serious Adverse Events makes clear that the tactics employed at the height of HIV/AIDS—the fearmongering, cancel culture, and “woke†takeover of science, medicine, and journalism—persist today. The response to COVID-19 isn’t new: it is a well-trod and dangerous path in the social landscape.  'Groundbreaking work.'—Bob Guccione, Jr., founder of SPIN magazine
Surviving HIV/AIDS in the Inner City explores the survival strategies of poor, HIV-positive Puerto Rican women by asking four key questions: Given their limited resources, how did they manage an illness as serious as HIV/AIDS? Did they look for alternatives to conventional medical treatment? Did the challenges they faced deprive them of self-determination, or could they help themselves and each other? What can we learn from these resourceful women? Based on her work with minority women living in Newark, New Jersey, Sabrina Marie Chase illuminates the hidden traps and land mines burdening our current health care system as a whole. For the women she studied, alliances with doctors, nurses, and social workers could literally mean the difference between life and death. By applying the theories of sociologist Pierre Bourdieu to the day-to-day experiences of HIV-positive Latinas, Chase explains why some struggled and even died while others flourished and thrived under difficult conditions. These gripping, true-life stories advocate for those living with chronic illness who depend on the health care "safety net." Through her exploration of life and death among Newark's resourceful women, Chase provides the groundwork for inciting positive change in the U.S. health care system.
The investigation of HAART adherence behavior and its effect on those under therapy in Uganda is important, especially because provision of HAART in low-income nations-such as those in sub-Saharan Africa, where many of the affected individuals are poverty stricken and possess little or no formal education-may result in negative public health implications, including those resulting from suboptimal adherence, such as drug resistance. In exploring the effect of HAART on sexual behavior of those under therapy, this study may augment existing knowledge pertaining to this area in resource-constrained nations. Of supreme importance, this study may assist in the formulation of strategies and policies that could enhance the effect of HAART and the quality of life for those with HIV/AIDS in developing nations such as Uganda.
This volume aims at presenting the latest international research and discoveries in the neurocognitive aspects and complications in HIV/AIDS, and how this understanding can shape and inform how we think about clinical practice and patient care in HIV/AIDS as well as lead to a better understanding of the underlying neuropathogenesis. The chapter, "Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders", of this book is available open access under a CC BY 4.0 license at link.springer.com
This comprehensive review examines the biological, medical, social, historical, and political aspects of HIV/AIDS. In AIDS, three Harvard-educated physicians explore the evolution of the HIV epidemic, contextualizing the disease from historical, social, and medical perspectives. Addressing the last 25 years, the book examines basic biological principles, including what a virus is, how the human immune system works, and how HIV impairs these functions. It presents an in-depth discussion of the HIV life cycle, explores central issues pertaining to diagnosis and treatment, and sheds light on how the treatment was developed and implemented. The book also reviews global epidemiology of HIV/AIDS and principles of transmission, as well as what comprises an epidemic and the factors that determine whether an infectious outbreak will propagate or die out. Finally, it looks at where HIV came from; early reactions to the disease and the social stigma it engendered; the cultural impact of HIV-positive role models; and the global economic, population, and political effects of this illness. Original stories about living with HIV penned by HIV-positive patients "Thought Boxes" and questions for discussion to challenge learners to think broadly and apply material presented in the book to other areas Case studies from China, Africa, and India Photographs taken by the author doing HIV work in Africa A chronology that traces the HIV epidemic from its discovery a quarter century ago
The surprisingly hopeful story of how a straight, nonpromiscuous, everyday girl contracted HIV and how she manages to stay upbeat, inspired, and more positive about life than ever before At nineteen years of age, Marvelyn Brown was lying in a stark white hospital bed at Tennessee Christian Medical Center, feeling hopeless. A former top track and basketball athlete, she was in the best shape of her life, but she was battling a sudden illness in the intensive care unit. Doctors had no idea what was going on. It never occurred to Brown that she might be HIV positive. Having unprotected sex with her Prince Charming had set into swift motion a set of circumstances that not only landed her in the fight of her life, but also alienated her from her community. Rather than give up, however, Brown found a reason to fight and a reason to live. The Naked Truth is an inspirational memoir that shares how an everyday teen refused to give up on herself, even as others would forsake her. More, it's a cautionary tale that every parent, guidance counselor, and young adult should read.
Since the first randomized controlled studies were conducted on medical circumcision to assess their effectiveness on reducing HIV transmission, health systems have made considerable progress in adopting this practice in their HIV/AIDS and sexual reproductive health policies. As such, medical circumcision is being adopted as an additional intervention measure to support previous practices for reducing HIV infections in various countries or settings. James Kityo's pioneering book examines contexts, processes, policy projections, and likely engagements by reviewing sexual reproductive health policies or practices, and literature on medical circumcision, and identifies existing opportunities and challenges. His book also explores the medical, gender, ethical, socio-economic, and human rights dimensions of medical circumcision as an HIV/AIDS prevention method. Following peer-reviewed studies, Kityo found compelling evidence documenting the effectiveness of medical circumcision in reducing HIV transmission, and discusses this evidence in the context of HIV/AIDS in a developing health system in Sub-Saharan Africa. The author concludes that there is a range of opportunities from research and current practice to enable policy makers to adopt medical circumcision and other interventions at their disposal in order to reduce infections from HIV and AIDS-related deaths. The author suggests feasible recommendations for implementing successful HIV/AIDS prevention programs in developing nations' health systems, including medical circumcision's gradual inclusion in health practices; stakeholder support; an elaborate review of this intervention by women, politicians, religious communities, and funding agencies. The author introduces a guided action plan, which can be used as a launch pad to enhance the learning process in the integration of medical circumcision in existing health practices.
Over the last several years the field of humanized mice has matured and developed into an essential component of translational research for HIV/AIDS. Humanized mice serve both as vehicles for discovery and as highly sophisticated platforms for biomedical research. In addition, humanized mice have demonstrated outstanding potential for the investigation of critical aspects of the infection and pathogenesis of the hepatitis and herpes viruses, as well as highly relevant microbial infections such as tuberculosis and malaria. Humanized Mice for HIV Research provides a comprehensive presentation of the history, evolution, applications, and current state of the art of this unique animal model. An expansion of twelve review articles that were published in Humanized Mice by Springer in 2008 (Eds: Nomura T, Watanabe T, Habu S), this book expertly captures the outstanding progress that has been made in the development, improvement, implementation, and validation of humanized mouse models. The first two parts of this book cover the basics of human-to-mouse xenotransplantation biology, and provide critical information about human immune cell development and function based on individual models created from different immunodeficient strains of mice. The third and fourth parts investigate HIV-1 biology, including different routes of transmission, prevention, treatment, pathogenesis, and the development of adaptive immunity in humanized mice. The fifth part shows the broad applicability of humanized mice for therapeutic development, from long-acting antiretroviral combinations to genetic manipulations with human cells and cell-based approaches. The sixth part includes liver tissue engineering and the expansion of humanized mice for many other human cell-tropic pathogens.
This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.
Written by a team of nationally recognized African American social work professionals with extensive and distinguished backgrounds of HIV/AIDS service, the book examines the crisis facing African American communities. The editors strive to convey to academics, researchers, and students the magnitude of the crisis and that individuals and organizations serving African Americans need to be able to respond to the service delivery needs this crisis brings. The crisis is evident in the fact that by year 2000 fully 50% of all AIDS cases will be among African Americans--who only constitute 12% of the nation's population. This book serves as a wake-up call and is designed to stimulate discussion and planning for new models of service to all African Americans and HIV prevention, education, and treatment. |
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