HIV/AIDS continues to be the pandemic of our times. It is estimated that 36 to 45 million people including 2-3 million children already are infected worldwide and an additional 4-7 million more are infected each year.
There has not been a comprehensive medically based AIDS prevention book published in the last five years. Since that time many new program interventions have been tried and much has been learned through evidence-based research. HIV Prevention will place special focus on the array of interventions that have been proven effective through rigorous study. If there is one theme that has been learned to date it is that there is no one-size-fits-all prevention approach that will work in all the geographic, demographic and socio-cultural environments impacted by the worldwide AIDS pandemic.
* Discusses all aspects of AIDS prevention, from epidemiology, molecular immunology and virology to the principles of broad-based public health prevention interventions.
* Special focus on the array of interventions that have been proven effective through rigorous study
* Identifies new trends in HIV/AID epidemiology and their impact on creating and implementing prevention interventions
* Incorporates virology, biology, infectious diseases, vaccinology, microbicides and research methodologies into AIDS prevention

"HIV alters the lives of anyone that it touches, whether they are gay or straight. This book looks at all of the aspects of how HIV/AIDS has altered the lives of those it touches. . . . The titles of the 12 chapters give an excellent overview of what is covered in these extremely well-written reports. . . . This is a must-read book for everyone. It should be in all libraries, including school libraries. Young adolescents who are facing the problem of coming out would benefit from this book." --AIDS Book Review Journal Hit hard by the AIDS epidemic in the United States and in much of Europe, the gay and lesbian community has been forced to examine existing notions of what it means to belong to a community based on sexual orientation. The editors of this second volume in the annual series Psychological Perspectives on Lesbian and Gay Issues have collected a perceptive array of chapters that explore sexual behavior, personal identity, and community memberships of gay men and lesbian women. With the exception of a few, the chapters reflect study findings from AIDS-related research and include discussions of AIDS in large urban centers and in less populated settings outside of major AIDS epicenters. Focusing on underconsidered AIDS populations, the contributors explore specific topics concerning the AIDS epidemic among gay and bisexual men of color, lesbian women, and gay and lesbian youth. Accessible and sensitive, the book also examines relevant public policy, volunteerism, and long-term survival as important to AIDS awareness and education. AIDS, Identity, and Community is an appreciable resource for AIDS researchers and caregivers, mental health practitioners, social service professionals, behavioral and social science students, and any reader who seeks deeper insight into the complex and subtle areas of the lesbian and gay community in the AIDS era.

While HIV spreads among people with severe mental illness for the same reasons it does in the general population, there are specific ways in which mental illness is associated with elevated HIV risk. Every mental health institution or program has to deal with the consequences of increased HIV rates, but until now there has been no single book that could tell them how to do so. AIDS and People with Severe Mental Illness covers the entire range of information essential for those who work with these patients: epidemiological, medical, psychological, legal, ethical, and policy issues are all examined by eminent authorities in those areas. Nurses, social workers, psychologists, psychiatrists, mental health administrators, forensic specialists, and others involved in the care of people with severe mental illness will find here exactly what they have been looking for: one handbook that can help them deal with the challenges the AIDS epidemic has set before them.

The major purpose of this book is to examine the interrelationships among knowledge about the transmission of HIV/AIDS, condom use, drug use, history of sexually transmitted diseases, and other relevant factors that affect African-American males and females who engage in risky sexual behaviors. Another aim is to describe how these factors are differentially related to gender and the perceived susceptibility of being exposed to the AIDS virus and testing positive for AIDS. Data has been gathered from a young adult sample of African-American males and females. Information is presented in a readily accessible manner so the reader can understand the variability of risky sexual behaviors. The author offers factual information to draw conclusions that can be used to develop HIV/AIDS prevention programs specifically tailored for the African-American community.

The first chapter provides an introduction, rationale, and overview of the study. Basic information about the prevalence of AIDS among various African-American populations are presented. Then, Johnson describes information about the subjects, measures of sexual behaviors, drug use, attitudes about the use of condoms, knowledge about AIDS, and perceived susceptibility of being exposed to HIV/AIDS. Next, Johnson describes the sexual attitudes and behaviors of African-American males and females who are currently involved with multiple partners and those who have been previously treated for sexually transmitted diseases. He then describes the characteristics of African-Americans with HIV/AIDS. The epilogue summarizes the major findings and presents suggestions for AIDS prevention activities for African-American young adults.

Although it is one of the most-widely studied viruses, many mysteries still remain about HIV. Covering the latest advances and challenges associated with clinical application of new antiviral drugs and vaccines, this revised edition is a companion to Murad: "HIV-1: Molecular Biology and Pathogenesis, 2E." Leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus.
* The latest developments in HIV-vaccine research
* New concepts in the discovery and design of novel anti-HIV drugs

This volume provides a comprehensive understanding of HIV/AIDS and neuro-AIDS, including a history of the disease, and an explanation of many of the conditions that can arise in afflicted patients, including opportunistic infections, central nervous system tumors, spinal cord disorders, myopathies and progressive encephalopathy, amongst others.

Clinicians will gain a greater understanding of the complex mechanisms of the disease. Beginning with a basic introduction to HIV infections and Neuro-AIDS, practitioners will find useful data on advances in molecular biology, neuroepidemiology, neuroimaging, neuropathology, neuropharmacology, as well as information on the development of therapeutic strategies appropriate for the disorder, including groundbreaking retroviral therapies.

In addition, the socioeconomic and political constraints that hinder treatment and disease management in developing parts of the world are presented.
* A comprehensive understanding of HIV/AIDS and neuro-AIDS, and the progression of the scientific community s understanding of the disease
* Detailed information on fields such as neuroepidemiology, neuropathology, neuropharmacology, and neuroimaging and their contributions to HIV/AIDS research
* Subject specific chapters on conditions associated with HIV/AIDS, including opportunistic infections, central nervous system tumors, and myopathies, amongst others"

A moving collection of firsthand accounts of the HIV epidemic. Tremendous strides have been made in the prevention and treatment of HIV since the disease first appeared in the 1980s. But because many of the people who studied and battled the virus in those early days are now gone, firsthand accounts are at risk of being lost. In HIV Pioneers, Wendee M. Wechsberg collects 29 "first stories" from the outset of the AIDS epidemic. These moving personal narratives and critical historical essays not only shed light on the experiences of global health pioneers, prominent scientists, and HIV survivors, but also preserve valuable lessons for managing the risk and impact of future epidemics. With unprecedented access to many key actors in the fight against AIDS and HIV, Wechsberg brings to life the harrowing reality of those early days of the epidemic. The book captures the experiences of those still working diligently and innovatively in the field, elevating the voices of doctors, scientists, and government bureaucrats alongside those of survivors and their loved ones. Focusing on the impact that the epidemic had on careers, pieces also show how governments responded to HIV, how research agendas were developed, and how AIDS service agencies and case management evolved. Illuminating the multiple facets of the HIV epidemic, both in the United States and across the globe, HIV Pioneers is a touching and inspirational look into the ongoing fight against HIV. Contributors: Quarraisha Abdool Karim, Salim S. Abdool Karim, Lynda Arnold, Anne Jeanene Bengoa, Robert E. Booth, Barry S. Brown, Thomas Coates, Francine Cournos, James W. Curran, Don C. Des Jarlais, Jeffrey D. Fisher, William A. Fisher, Samuel R. Friedman, Robert C. Gallo, Mary Guinan, Gibbie Harris, Warren W. Hewitt Jr., Susan M. Kegeles, Rayford Kytle, Bishop Stacey S. Latimer, Robert Love, Duane C. McBride, Clyde B. McCoy, Carmen Morris, Willo Pequegnat, Mary Jane Rotheram-Borus, Jeffrey Samet, David Serwadda, Lorraine Sherr, James L. Sorensen, Jack B. Stein, Charles van der Horst, Wendee M. Wechsberg, Wayne Wiebel, William A. Zule

In June 1981, the Centers for Disease Control and Prevention reported the first evidence of a new disease that would later become known as Acquired Immunodeficiency Syndrome (AIDS). HIV and Aids: Basic Elements and Priorities is a concise collection of all aspects of this disease and a source of readily available knowledge. It examines all currently advocated preventive measures such as health education, condom use, safer sex practices, and treatment of sexually transmitted infections. Coverage includes: up-to-date information on multiple dimensions of the HIV/AIDS epidemic; a discussion on new anti-retroviral therapy/drugs, new drugs under clinical trials and preventive HIV vaccine; coverage of current ethical, legal and social issues related to HIV/AIDS; an evaluation of general public awareness about HIV/AIDS; a global perspective and information about HIV/AIDS.

The author of the bestselling The City of Joy presents the tender, inspiring adventure of the scientists, doctors, nurses, victims, and Sisters of Mother Teresa who are battling against the dread epidemic of AIDS. LG Featured Alternate.

Entry Inhibitors in HIV Therapy details the current status of this relatively new and very dynamic class of inhibitors, appealing to both the clinician and basic research scientist. A unique overview of obstacles and accomplishments is presented. The book features chapters that explain the challenges of high sequence diversity in the viral envelope gene for the development and use of entry inhibitors, the clinical utility of virus phenotyping, the development of this class of inhibitors as microbicidal therapy, and the success story of enfuvirtide from the bench to FDA approval. Both basic research findings and results of clinical studies are covered and linked together by a diverse panel of experts in the field.

One Sunday in February 1987, protesters stood outside the Unitarian Universalist Church of Amherst in Massachusetts, whose minister planned to hand out condoms during his sermon, dramatizing the need for the church to confront the AIDS crisis. The minister gave out nearly five hundred condoms as the audience exploded into applause. But he could not hang around to enjoy it; having received threats in advance of the service, he dashed out of the sanctuary immediately. Thus was the climate for religious AIDS activism in the mid-1980s. After the Wrath of God is the first book to tell the story of American religion and the AIDS epidemic. Anthony Petro shows how religious leaders and organizations posited AIDS as a religious and moral epidemic, and analyzes how this construction has informed cultural and political debates about public health and sexual morality. While most attention to religion and AIDS foregrounds the role of the Religious Right, this book examines the much broader-and more influential-range of mainline Protestant, evangelical, and Catholic groups that shaped public discussions of AIDS prevention and care in the U.S. The AIDS epidemic, Petro argues, effected a shift in Christian rhetoric regarding sexuality. Mainstream religious groups almost uniformly called for compassion for those afflicted with the disease. While the Christian Right focused on what not to do, an increasing number of mainstream religious leaders promoted instead a positive prescription for sex, one more readily taken up in public health endeavors and sex education curricula alike-a vision that informs debates over sexual morality to this day.

Asia has become the new battle ground for the war against HIV/AIDS. The magnitude of the potential public health problems caused by AIDS in this populous continent may become a catastrophic disaster. A 10% rate of prevalence of HIV-1 in India and China alone would mean more than 200 million people are infected with HIV.
AIDS in Asia is useful as a comprehensive, up-to-date AIDS reference book for public health and medical professionals. This volume provides concrete information on the diagnosis, treatment, care, prevention and impact of AIDS. Part I contains 'Snapshots of HIV/AIDS in Asia.' Countries and regions included in this section are: Thailand, India, China, Japan, Vietnam, Laos, Cambodia, Myanmar, Malaysia, Indonesia, the Philippines, Pakistan, Nepal, Sri Lanka, Hawaii and the Pacific Islands, Hong Kong and Taiwan. Part II addresses the molecular epidemiology of HIV/AIDS. Part III deals with the diagnosis, surveillance and projected scenarios of the AIDS epidemic. Part IV outlines prevention efforts and treatment options. Part V provides an overview of the ongoing collaborative efforts involved in several different nations in the worldwide war against AIDS.
This volume will be invaluable to all the public health professionals and researchers working in this field.

..".the book is a useful addition to the HIV/AIDS literature."

"AIDS in Asia offers a comprehensive, interesting overview of the epidemic there and of general issues that will influence its progression."

-Roger Detels, MD, MS, University of California-Los Angeles

The Journal of the American Medical Association, Book Review, 293:15

Computational and Evolutionary Analysis of HIV Molecular Sequences is for all researchers interested in HIV research, even those who only have a nodding acquaintance with computational biology (or those who are familiar with some, but not all, aspects of the field). HIV research is unusual in that it brings together scientists from a wide range of disciplines: clinicians, pathologists, immunologists, epidemiologists, virologists, computational biologists, structural biologists, evolutionary biologists, statisticians and mathematicians. This book seeks to bridge the gap between these groups, in both subject matter and terminology. Focused largely on HIV genetic variation, Computational and Evolutionary Analysis of HIV Molecular Sequences covers such issues as sampling and processing sequences, population genetics, phylogenetics and drug targets.

This wide-ranging volume reviews the experience and treatment of HIV/AIDS in rural America at the clinical, care system, community, and individual levels. Rural HIV-related phenomena are explored within healthcare contexts (physician shortages, treatment disparities) and the social environment (stigma, the opioid epidemic), and contrasted with urban frames of reference. Contributors present latest findings on HIV medications, best practices, and innovative opportunities for improving care and care settings, plus invaluable first-person perspective on the intersectionality of patient subpopulations. These chapters offer both seasoned and training practitioners a thorough grounding in the unique challenges of providing appropriate and effective services in the region. Featured topics include: Case study: Georgia's rural vs. non-rural populations HIV medications: how they work and why they fail Pediatric/adolescent HIV: legal and ethical issues Our experience: HIV-positive African-American women in the Deep South Learning to age successfully with HIV Bringing important detail to an often-marginalized population, HIV/AIDS in Rural Communities will interest and inspire healthcare practitioners including physicians, nurse practitioners, physician assistants, pharmacists, case managers, psychologists, social workers, counselors, and family therapists, as well as educators, students, persons living with HIV, advocates, community leaders, and policymakers.

Forty years ago, the age-old battle against infectious diseases as a major threat to human health was believed close to being won. However, by the late twentieth century, the increase of emerging and reemerging infectious diseases was evident in both low and high income countries. About 30 new infectious diseases have been identified in the last 20 years. Among the a oenewa diseases, and most importantly, the Human Immunodeficiency Virus (HIV) epidemic, with 40 million persons infected and 25 million deaths since its first description, presents one of the most significant health, societal and security challenges facing the global community. The interaction of HIV/AIDS with tuberculosis, malaria and bacterial infections have increased HIV-related morbidity and mortality, and in turn, the HIV pandemic has brought about devastating increases in tuberculosis.

Understanding the population impact and the dynamics of infection diseases in the most affected region is critical to efforts to reduce the morbidity and mortality of such infections, and for decisions on where to use limited resources in the fight against infections.

This book aims to contribute to these efforts by offering a demographic and epidemiological perspective on emerging and reemerging infections in sub-Saharan Africa.

Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS). The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.

The development of proteomic analyses using advanced mass spectrometry techniques has revolutionized the way proteins are studied, namely, as individual molecules within a complex system. HIV-1 Proteomics: From Discovery to Clinical Application comprehensively covers protein analysis from the early classic experimental days to current state-of-the-art HIV-1 proteomics in a clear informative style that brings expert-level understanding to the novice. Discussion of important clinical applications and future directions for the field also make this an ideal read for the expert. After finishing this book, the reader will have a complete and functional understanding of protein analysis from traditional biochemistry to modern proteomics.

HIV and the New Viruses presents cutting-edge reviews of persistent human virus infections as a coherent collection for the first time. These cover recently discovered viruses such as HHV-6, HHV-8 and HCV, as well as the latest research on HIV.
This comprehensive and updated reference includes an in-depth study of the major issues in the epidemiology, pathogenicity, molecular virology, host responses and management of conditions associated with those viruses. Information on new pharmaceuticals and vaccine developments is also included.
Edited by the leading experts in the field, HIV and the New Viruses will be essential reading for postgraduates, clinicians and researchers in virology, immunology, cancer, molecular biology and the pharmaceutical industry.
Key Features
* Presents cutting-edge reviews of persistent human virus infections as a coherent collection for the first time
* Includes an in-depth study of the major issues in the epidemiology, pathogenicity, molecular virology, host responses, and management of conditions associated with those viruses