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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > HIV / AIDS
The AIDS crisis reshaped life in Los Angeles in the 1980s and 1990s and radicalized a new generation of queer Asian Americans with a broad vision of health equity and sexual freedom. Even amid the fear and grief, Asian American AIDS activists created an infrastructure of care that centered the most stigmatized and provided diverse immigrant communities with the health resources and information they needed. Without a formal blueprint, these young organizers often had to be creative and agitational, and together they reclaimed the pleasure in sex and fostered inclusivity, regardless of HIV status. A community memoir, Love Your Asian Body connects the deeply personal with the uncompromisingly political in telling the stories of more than thirty Asian American AIDS activists. In those early years of the epidemic, these activists became caregivers, social workers, nurses, researchers, and advocates for those living with HIV. And for many, the AIDS epidemic sparked the beginning of their continued work to build multiracial coalitions and confront broader systemic inequities. Detailing the intertwined realities of race and sexuality in AIDS activism, Love Your Asian Body offers a vital portrait of a movement founded on joy.
This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.
This book on NeuroAIDS, a collection of chapters written by experts and specialists from around the world, provides a global perspective on HIV and NeuroAIDS in the field, clinic, and laboratory. The chapters address the comorbidity of HIV and other infectious agents, including Zika virus, Ebola, Chagas disease, TB and HCV. Also discussed are key topics, such as: * Molecular socioepidemiology * Global HIV and NeuroAIDS * Neuropathology * cART and blood-brain barrier penetration * HIV replicative oscillations * HIV and SIV evolution * Psychiatric comorbidities * Neurosyphilis * The examination of current and innovative models of translational research to translational effectiveness
A collection of original papers on the nature of AIDS social research, this volume brings together anthropologists, sociologists, psychologists, and public health researchers to consider the methodological, empirical, and conceptual aspects of the problem. Unlike other studies, which focus on the medical and epidemiological aspects of AIDS, this study specifically focuses on the social aspects of the disease, the response of the community and medical profession, and the effects of the epidemic upon the gay subculture. Consideration is given to methodological shortcomings in the research on the social aspects of AIDS as well as reports of original research.
Since the AIDS epidemic was recognized, information on safer sex has been assumed to be the most crucial means of preventing further spread of the disease. But how well has AIDS education worked? What kinds of education work best and for whom? This study is the first to provide an in-depth analysis of the results of AIDS education programs and to explore the psychosocial factors that affect behavioral responses to education. B. R. Simon Rosser provides a detailed profile of a specific population at risk, including factors such as sexual behavior, psychology, religious affiliation, legal status, and discrimination. Using comparative measures of behavior, personality, social status, attitudes, and risk-taking, he identifies important differences between homosexual men who engage in safer sex and those who do not. Finally, he evaluates the impact of different approaches to AIDS education. Examining both positive and negative effects, Rosser shows that the spread of the HIV virus was actually accelerated by a national education campaign utilizing fear, and contrasts this result with four international gay-sensitive education campaigns that produced positive changes in behavior and lifestyle. He discusses ways in which AIDS education must develop in order to become more effective, together with crucial changes that are needed in both the gay population and the larger community if HIV transmission is to be halted. This study is a valuable resource for education and research in AIDS prevention, sexual behavior, psychovenereology, education, health, and related disciplines.
This ambitious book provides a comprehensive history of the World Health Organization (WHO) Global Programme on AIDS (GPA), using it as a unique lens to trace the global response to the AIDS pandemic. The authors describe how WHO came initially to assume leadership of the global response, relate the strategies and approaches WHO employed over the years, and expound on the factors that led to the Programme's demise and subsequent formation of the Joint United Nations Programme on HIV/AIDS(UNAIDS). The authors examine the global impact of this momentous transition, portray the current status of the global response to AIDS, and explore the precarious situation that WHO finds itself in today as a lead United Nations agency in global health. Several aspects of the global response - the strategies adopted, the roads taken and not taken, and the lessons learned - can provide helpful guidance to the global health community as it continues tackling the AIDS pandemic and confronts future global pandemics. Included in the coverage: The response before the global response Building and coordinating a multi-sectoral response Containing the global spread of HIV Addressing stigma, discrimination, and human rights Rethinking global AIDS governance UNAIDS and its place in the global response The AIDS Pandemic: Searching for a Global Response recounts the global response to the AIDS pandemic from its inception to today. Policymakers, students, faculty, journalists, researchers, and health professionals interested in HIV/AIDS, global health, global pandemics, and the history of medicine will find it highly compelling and consequential. It will also interest those involved in global affairs, global governance, international relations, and international development.
This book tells the story of the HIV epidemic in South Africa, and asks why, after more than three decades, it has not normalised. Despite considerable efforts to prevent infection, and ambitious targets set to end the epidemic by 2030, HIV infections are increasing among young women and treatment uptake and adherence have been uneven. Focusing on the years preceding and following treatment access, this book addresses why an end to AIDS may be misplaced optimism. By examining public discourses and private narratives about infection, illness and death, this work reveals the contradictions between the lived experiences of AIDS suffering on the one hand, and biomedical certainties on the other. Based on long-term ethnographic research in rural villages of the South African lowveld, and within HIV prevention interventions in South Africa more generally, this book offers an intimate perspective on the social and cultural responses to the epidemic.
Linked by Blood: Hemophilia and AIDS recounts the factors responsible for the widespread infection of people with hemophilia by Human Immunodeficiency Virus (HIV)-contaminated blood and offers a prescription for addressing the challenges of future viral epidemics. The book describes the impact of AIDS on people with hemophilia, their families, and caregivers. The collection, processing, and distribution of blood in the early years of the HIV epidemic are described, including the failure of regulatory agencies to promulgate effective rules to safeguard the blood supply. The contributions of individuals and organizations that mitigated the epidemic are recognized. Linked by Blood presents recommendations for addressing the myriad medical, social, and economic challenges posed by blood-borne viral infections (AIDS, Ebola, MERS) that periodically sweep through large segments of our population.
What happens to national HIV programmes when Science and Religion collide and when both ignore the setting of most infections: in or on the way to marriage? HIV and AIDS are serious social and public-health problems in Papua New Guinea. After long delays, community-, business- and faith-based organizations have launched an impressive multi-sectoral response. But health-service systems are overwhelmed by the need for HIV antibody testing and counselling, and for treatment with antiretrovirals. Foreign notions of epidemiology, such as 'sex worker', 'risk group' and 'rural/urban', have gained traction despite massive empirical evidence as to their inapplicability. Each of these has fuelled, rather than confronted, the gendered contradictions of marriage and sexuality in Papua New Guinea. Quantitative approaches have fetishized numbers at the expense of enabling changes in social-structure. Part One of Sin, Sex and Stigma draws upon ethnography, public discourse and archival data to critique public-health policy and epidemiological modelling. Christian-inflected sex-negativity and anti-condom rhetoric are shown to have stymied prevention initiatives. Part Two enlists experts in antiretroviral therapy, sex work activism and ethnography in dialogues focused on strengthening the national response to HIV and AIDS. 'A "hot glow of anger" compelled Lawrence Hammar to write this fiery account of the many factors preventing successful HIV and AIDS interventions in Papua New Guinea. Drawing on his extensive research experience on sexuality and sex work, on cultural and Christian ideologies, and on outrageous stories of denial, abuse, and stigma, Hammar paints a rich and devastating portrait of the history of AIDS in PNG. Read it and weep. Lawrence Hammar is an inspiring reminder for AIDS scholars and activists everywhere of the differences committed social scientists can make to the way things are done.', Leslie Butt, Dept. of Pacific and Asian Studies, University of Victoria
This book delves into this almost unchartered territory, documenting the lived experiences of sex workers in Bangladesh, considering the complex realities of their day-to-day lives and the ways they negotiate their working conditions and relationships. Despite being the most common form of female deviance and criminality globally, we know very little about sex work in Asia and the global south. Drawing on feminist frameworks, it shows that the experiences of sex workers vary widely depending on the ways they enter the sex trade, their modes of operation, and relationships with significant others. Towards a Southern Approach to Sex Work contributes to feminist scholarship on sex work, by offering a much needed southern perspective, drawing on culturally specific data. It argues that the lived experience of sex workers comprises both victimhood and agency, deception and resilience, and that it is the management of these relationships that enable sex works to avoid social marginalization and alienation. An accessible and compelling read, this will appeal to students and scholars of criminology, sociology, gender studies, south Asian studies, cultural studies, social theory and policy makers. In addition, it will engage all those interested in learning more about how the sex trade operates in Bangladesh.
* One of the first books in the new Leading Conversations in Black Sexualities and Identities series. * Explores various psychosocial, sociocultural, and contextual factors critical among Black college students within the milieu of HBCUs, and how this environment can promote sexual health. * Essential reading for public health and social science researchers and practitioners, as well as student affairs and campus wellness centers. * Aims to help the development of strategies and interventions to improve sexual health outcomes amongst black students at HBCUs, and advance the translation of culturally grounded research into effective practice.
Immunopathology, Diagnosis and Treatment of HPV induced Malignancies focuses on the human papilloma virus infection and associated cancers. In ten chapters, the book explains the deep knowledge about molecular mechanism in HPV pathogenesis and recent advanced tools applied in the field of HPV induced cancer and cures. In a nutshell, the book gives new insights and the associated challenges involved in the identification of promising drug and vaccine targets, current diagnostic tools, and advancements in current therapies against HPV induced cancers and other malignancies.
This book provides an overview of the social, economic, and political impact of AIDS around the world. The sudden appearance and rapid spread of AIDS has given birth to an enormous amount of literature. This volume summarizes recent writings about AIDS and provides a framework for thinking about the eventual consequences of this world-wide epidemic. As an interdisciplinary work, this text draws upon research from diverse fields, such as anthropology, demography, economics, epidemiology, history, political science, public health, social psychology, and sociology. The volume begins with a look at the spread of AIDS and its prevalence throughout the developing world. Special attention is given to AIDS in the United States in one chapter, and other chapters discuss the international response to AIDS, including public and government reactions.
This book considers the change in rhetoric surrounding the treatment of AIDS from one of crisis to that of 'ending AIDS'. Exploring what it means to 'end AIDS' and how responsibility is framed in this new discourse, the author considers the tensions generated between the individual and the state in terms of notions such as risk, responsibility and prevention. Based on analyses public health promotions in the UK and the US, HIV prevention science and engaging with the work of Foucault, this volume argues that the discourse of 'ending AIDS' implies a tension-filled space in which global principles and values may clash with localised needs, values and concerns; in which evidence-based policies strive for hegemony over local, tacit and communal regimes of knowledge; and in which desires compete with national and international ideas about what is best for the individual in the name of 'ending AIDS' writ large. As such, it will appeal to scholars of sociology and media studies with interests in the sociology of medicine and health, medical communication and health policy.
This book will be a vital resource for researchers in the field of health communication, especially in the aftermath of COVID-19, as we begin confronting the reality of which countries can afford to declare an 'end to the pandemic', and which ones can't A unique feature of this book is that its center and focus is on persons living with HIV - It highlights their experiences and voices It examines the discourse of a "post-AIDS" culture using a range of methodological tools, and the medical-discursive shift from crisis and death to survival and living It includes contributions from a diverse group of international scholars, and interrogates and engages with the cultural, social, political, scientific, historical, global, and local consumptions of the term "post-AIDS" from the perspective of meaning-making on health, illness, and well-being This book will be an essential read for scholars and students of health communication, sociology of health and illness, medical humanities, political science, and medical anthropology, as well as for policy makers and activists
Access the latest information available in the challenging area of HIV/AIDS management with Sande's HIV/AIDS Medicine, 2nd Edition. Authored by a veritable "who's who" of current global experts in the field, this medical reference book will provide you with all the practical, indispensable guidance you'll need to offer your patients the best possible care. Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers. Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS epidemic and the different needs of Western vs. developing-world patients and clinicians. Diagnose AIDS manifestations confidently by comparing them to clinical images. Improve patient outcomes with the latest findings on the management of AIDS as a chronic illness. Efficiently review essential data through numerous at-a-glance tables. Get the most relevant information available on pediatric HIV and AIDS issues; anti-retroviral drugs, including integrase inhibitors; and the use of second- and third-line anti-retroviral drugs in resource-poor settings. Stay current on the latest actionable information, such as using antiretroviral therapy in patients with tuberculosis and drug-resistant tuberculosis; antiretroviral therapy; immune reconstitution inflammatory syndromes (IRIS); and implementation of the HPV vaccine. The very latest in HIV/AIDS management from global experts with a concise approach and a clinical/practical focus.
-Accessible introduction to the full spectrum of diseases and disasters for students of politics, human security studies and development studies -Case studies include Covid-19, Haiti Earthquake 2010, Hurricane Maria, Typhoon Haiyan, Second Congo War; Yemen Civil War; Tajikistan Civil War, AIDS in Africa, Malaria, SARS, and Ebola -Timely new textbook to address issues arising from the Covid-19 global pandemic
This book addresses the impact of HIV on populations of men who have sex with men in Africa and local responses to the issue. It documents the enduring existence of a rich variety of same-sex practices between men. More critically, it analyses how the denial and social rejection of same-sex sexuality, together with the legacy of criminalization by former colonial rulers, has not only fueled the transmission of HIV between men, but has also impeded an effective response. The book also documents some of the outstanding progress that has been made and acknowledges the differences between African countries. Through its focus on lived realities and grassroots activism in Africa, this book will appeal to researchers, policy makers and practitioners alike.
The association between AIDS and cancer was recognized from the beginning of the AIDS epidemic, when the appearance of Kaposi sarcoma in a cluster of young men was one of the first signs of this new disease. It was soon recognized that AIDS was caused by infection with a novel virus (HIV) and that AIDS patients are prone to develop a number of "AIDS-defining" cancers: Kaposi sarcoma, lymphoma, and cervical cancer. The development of effective combination anti-HIV therapy starting around 1996 converted AIDS from a death sentence to a manageable disease and led to dramatic shifts in the epidemic. As this therapy was able to improve immune function in patients, the incidence of most "AIDS-defining" cancers decreased. There is a misconception, however, that AIDS has gone away. In fact, as AIDS patients are living longer, the number of AIDS patients has more than doubled in the United States since 1996, and the AIDS population overall has increased in age. Also, as AIDS patients are less likely to die of other complications, cancer is coming to the forefront as one of the most common causes of death in regions where AIDS drugs are widely available. Moreover, the three "AIDS-defining" cancers are now taking a back seat to a number of other HIV-associated cancers, such as Hodgkin lymphoma, lung cancer, and anal cancer. In the developing world, AIDS-associated cancers are a major public health problem, and in some regions of sub-Saharan Africa, Kaposi sarcoma is the most common tumor in men. In recent years, there has been a vast increase in our understanding of HIV-associated cancers. We now know, for example, that most are caused by other viruses and that the main role of HIV and immunodeficiency is to provide a supportive environment for the viruses to multiply and for the cancers to develop. But there remain a number of unanswered questions and a need for improved prevention and therapy. In the 28 chapters of this book, written by some of the most renowned experts in this field, we present up-to-date information on the cancers associated with HIV infection. The chapters cover the epidemiology of these cancers, their pathogenesis, their clinical presentation, and their treatment. The book will be of value to physicians, other medical professionals, students, and researchers with an interest in AIDS, viral-associated cancers, or HIV-associated malignancies. TABLE OF CONTENTS 1. HIV-associated Cancers: Overview Robert Yarchoan, Thomas Uldrick, Mark Polizotto 2. Epidemiology of AIDS-defining Malignancies William A. Blattner and Rebecca G. Nowak 3. Epidemiology of non-AIDS Defining Malignancies Andrew E. Grulich 4. HIV Cancers in Resource-Limited Regions Sam M. Mbulaiteye 5. Kaposi's Sarcoma-associated Herpesvirus (KSHV) Blossom Damania and Dirk P. Dittmer 6. Epstein Barr Virus (EBV) Lindsey Hutt-Fletcher 7. Human Papillomavirus (HPV) Zhi-Ming Zheng 8. Merkel Cell Polymavirus (MCV) Nicole Fischer and Adam Grundhoff 9. Presentation and Pathogenesis of Kaposi's Sarcoma Corey Casper 10. Management of Kaposi's Sarcoma Susan E. Krown 11. Presentation and Pathogenesis of HIV Lymphomas Richard F. Little, Stefania Pittaluga, Kieron Dunleavy 12. Diffuse Large B-Cell Lymphoma Neel K. Gupta and Lawrence D. Kaplan 13. Burkitt and Burkitt-Like Lymphoma Kishor Bhatia and Sam M. Mbulaiteye 14. Primary Effusion Lymphoma Giovanna Tosato 15. AIDS-related Central Nervous System Lymphoma Jan Davidson-Moncada and Thomas Uldrick 16. Plasmablastic and Other Lymphomas Huan-You Wang, Ida Wong-Sefidan, Erin Reid 17. Hodkin Lymphoma Michele Spina, Rosanna Ciancia, Accursio Augello 18. Multicentric Castelman Disease Mark N. Polizzotto, Thomas S. Uldrick, Robert Yarchoan 19. Cervical Cancer Elizabeth A. Stier 20. Anal Cancer Joel Palefsky 21. Other HPV-Associated Cancers Kristina R. Dahlstrom and Erich M. Sturgis 22. Lung Cancer in HIV Infection Deepthi Mani and David M. Aboulafia 23. Hepattocellular Carcinoma in HIV-positive Patients Massimiliano Berretta, Paolo De Paoli, Umberto Tirelli, Bruno Cacopardo 24. Merkel Cell Carcinoma and Other HIV-associated Skin Cancers Nathalie C. Zeitouni adn Bethany Lema 25. Conjuctival Carcinoma Kenneth O. Simbiri and Erle S. Robertson 26. Malignancies in Children with HIV Infection D. Cristina Stefan 27. cART and Supportive Care Ronald T. Mitsuyasu 28. Stem Cell Transplantation Christine Durand and Richard Ambinder
Social work practitioners active among those most directly involved with persons with AIDS/HIV need guidance and support. This volume offers both in a balanced analysis of key issues relating to their practice. The authors clearly and authoritatively establish that the demographics of the AIDS/HIV crisis are undergoing change rapidly and alarmingly. Although there have been significant advances in education about AIDS and modifications in sexual practices among gay men resulting in a lowered rate of new infection, other groups are shown to be evidencing explosive levels of infection. Not only are the population parameters of AIDS defined, but the fundamental issues of social service delivery are addressed as are the special needs of the newly at-risk groups. Women, adolescents, substance abusers, minorities, and the mentally ill are all in the demographic patterns describing AIDS/HIV diffusion. The most compelling AIDS care issues are directly focused on and practical guidance is given to social work practitioners. AIDS/HIV poses a sometimes daunting challenge threatening to overwhelm service providers. This book will be of value due to its sensitive, insightful, experience-based guidance at the level of practice. It will also prove a useful resource for all in the caring professions who will appreciate its timely explanation of the complexities involved in framing effective responses to current and emerging needs associated with AIDS/HIV.
The world continues to lose more than a million lives each year to the HIV epidemic, and nearly two million individuals were infected with HIV in 2017 alone. The new Sustainable Development Goals, adopted by countries of the United Nations in September 2015, include a commitment to end the AIDS epidemic by 2030. Considerable emphasis on prevention of new infections and treatment of those living with HIV will be needed to make this goal achievable. With nearly 37 million people now living with HIV, it is a communicable disease that behaves like a noncommunicable disease. Nutritional management is integral to comprehensive HIV care and treatment. Improved nutritional status and weight gain can increase recovery and strength of individuals living with HIV/AIDS, improve dietary diversity and caloric intake, and improve quality of life. This book highlights evidence-based research linking nutrition and HIV and identifies research gaps to inform the development of guidelines and policies for the United Nations' Sustainable Development Goals. A comprehensive approach that includes nutritional interventions is likely to maximize the benefit of antiretroviral therapy in preventing HIV disease progression and other adverse outcomes in HIV-infected men and women. Modification of nutritional status has been shown to enhance the quality of life of those suffering HIV/AIDS, both physically in terms of improved body mass index and immunological markers, and psychologically, by improving symptoms of depression. While the primary focus for those infected should remain on antiretroviral treatment and increasing its availability and coverage, improvement of nutritional status plays a complementary role in the management of HIV infection.
The study of viruses necessarily involves dissecting the intimate details of cellular pathways. Viruses have often been employed as tools in studying cellular pathways, as was done by early retrovirologists such as Peyton Rous in attempting to understand the mechanism of cellular transformation and oncogenesis. On the other side of the coin, virologists seek to de?ne those cellular elements interacting intimatelywiththeir virus ofinterestinorder to better understand viral replication itself, and in some cases to develop antiviral strategies. It is in the intersection of virology and cell biology that many of us ?nd the most rewarding aspects of our research. When a new discovery yields insights into basic cellular mechanisms and presents new targets for int- vention to ?ght a serious pathogen, the impact can be high and the excitement intense. HIV has been no exception to the rule that viruses reveal many basic aspects of cellular biology. In recent years, in part because of the importance of HIV as a major cause of human suffering, numerous cellular processes have been elucidated through work on processes or proteins of this human retrovirus. The excitement in this ?eld is especially well illustrated by the discovery of new innate means of resisting viral replication, such as the work on APOBEC3G, TRIM5a, and BST-2/ tetherin presented in this volume.
Urban Action Networks is a study of how communities organize in response to threats to their lives and well being. As HIV/AIDS wreaked havoc on the worlds of some of the most marginal and disenfranchised people in New York, they came together to create a shared response, forming a new organizational field within which their various efforts were coordinated. This book traces the interorganizational processes by which the groups negotiated shared meanings, collective strategies, and a complex, shifting set of relations with local and national government. It covers the first decade of AIDS, when the organized community groups actively set the agenda. How the communities of the most affected people organized, reorganized, and redefined the social and political context of HIV/AIDS offers an encouraging glimpse into the way in which marginal communities can convert shared needs into collective action. |
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