According to the Centers for Disease Control and Prevention, young people aged 18 to 25 are at a significant risk for acquiring and transmitting HIV (Human Immunodeficiency Virus) and other STIs (sexually transmitted infections). Primary developmental processes that place college students particularly at risk include the experience of intimacy, sexual desires and the centrality of the peer group. During these routine developmental processes, college students experiment with unprotected sex, multiple sex partners and alcohol and illicit drugs, all of which are contributing risk factors for HIV/STI infections.

Early diagnosis, treatment and prevention of HIV and other STIs is germane to promoting the sexual health of college students and reducing high HIV/STI infection rates among young people. This edited volume will provide innovative and cutting-edge approaches to prevention for college students and will have a major impact on advancing the interdisciplinary fields of higher education and public health. It will explore core ideas such as hooking up culture, sexual violence, LGBT and students of color, as well as HIV and STI prevention in community colleges, rural colleges and minority serving institutions."

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For young gay men who came of age in the United States in the 1980s, the HIV/AIDS epidemic was a formative experience in fear, hardship, and loss. Those who were diagnosed before 1996 suffered an exceptionally high rate of mortality, and the survivors - both the infected individuals and those close to them - today constitute a "bravest generation" in American history. The AIDS Generation: Stories of Survival and Resilience examines the strategies for survival and coping employed by these HIV-positive gay men, who together constitute the first generation of long-term survivors of the disease. Through interviews conducted by the author, it narrates the stories of gay men who have survived since the early days of the epidemic; documents and delineates the strategies and behaviors enacted by men of this generation to survive it; and examines the extent to which these approaches to survival inform and are informed by the broad body of literature on resilience and health. The stories and strategies detailed here, all used to combat the profound physical, emotional, and social challenges faced by those in the crosshairs of the AIDS epidemic, provide a gateway for understanding how individuals cope with chronic and life-threatening diseases. Halkitis takes readers on a journey of first-hand data collection (the interviews themselves), the popular culture representations of these phenomena, and his own experiences as one of the men of the AIDS generation. This riveting account will be of interest to health practitioners and historians throughout the clinical and social sciences - or to anyone with an interest in this important chapter in social history.

In 1999, investigators announced that a single dose of nevirapine, a new antiviral drug, could stop the spread of the AIDS virus from infected mothers to their newborn babies. It was a discovery that ""changed the face of AIDS globally"" but it came at a high price, after years of scientific research, political conflict, social unrest and the loss of many thousands of lives. This book is the historical account of pediatric AIDS from the first reported cases in the early 1980s to the first effective treatments in the 1990s and then to the prevention of HIV infections altogether. It tells the story through the experiences of individual children infected with HIV, their families and the physicians who treated them, as well as the scientists who sought to understand the virus, discovered nevirapine's unique properties, and worked tirelessly to get it to the patients who needed it.

This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.

It is now forty years since the discovery of AIDS, but its origins continue to puzzle doctors, scientists and patients. Inspired by his own experiences working as a physician in a bush hospital in Zaire, Jacques Pepin looks back to the early twentieth-century events in central Africa that triggered the emergence of HIV/AIDS and traces its subsequent development into the most dramatic and destructive epidemic of modern times. He shows how the disease was first transmitted from chimpanzees to man and then how military campaigns, urbanisation, prostitution and large-scale colonial medical interventions intended to eradicate tropical diseases combined to disastrous effect to fuel the spread of the virus from its origins in Leopoldville to the rest of Africa, the Caribbean and ultimately worldwide. This is an essential perspective on HIV/AIDS and on the lessons that must be learned as the world faces another pandemic.

Despite effective approaches to prevention, STD and HIV infection rates remain fairly constant. Targeting, implementation, and monitoring of interventions have posed widespread problems, and the recent spate of cuts to prevention budgets has made these roadblocks even more challenging. It is clear that working in sexual health requires both a deeper understanding of STI/HIV epidemiology and an ongoing quest for up-to-date, realistic prevention strategies. The New Public Health and STD/HIV Prevention offers readers leading-edge access to both. Focusing on social determinants of sexual health, at-risk populations, critical factors in approaches to prevention, and reviews of new research, this authoritative volume explores areas as varied as HPV prevention, technology-based interventions, migration as a factor in disease transmission, and competencies key to effective leadership in the field. Dispatches from the frontlines of theory, research, and practice in the U.S. and abroad include: Personal risk, public impact: balancing individual rights and STD/HIV prevention. Distribution of prevention resources and its impact on sexual health. Prevention measures in diverse populations of women. Toward a better approach to preventive interventions with men who have sex with men. Adolescent sexual health and STIs. Reducing disparities in sexual health: lessons from the campaign to eliminate infectious syphilis. Public health professionals of all backgrounds interested in or working in improving sexual health will find The New Public Health and STD/HIV Prevention an indispensable guide to conceptualizing the problems and clarifying possible solutions.

When Communities Assess their AIDS Epidemics is a detailed ethnographic description of the AIDS epidemic in ten U.S. cities and the U.S. Virgin Islands. Employing a rapid ethnographic assessment methodology, cities from the Atlantic to the Pacific have implemented Project RARE (Rapid Assessment, Response, and Evaluation) efforts. These RARE projects examine the moving edge of the AIDS epidemic through descriptions of high-risk sites and identifications of segments of the populations at greatest risk. Utilizing a series of focus groups and street interviews, local field research teams gain an insider's perspective on HIV risk within social contexts. Dr. Benjamin P. Bowser, Dr. Ernest Quimby, and Dr. Merrill Singer have compiled these critical studies that analyze current conditions, challenges, and recommendations encountered by RARE. When Communities Assess their AIDS Epidemics is a powerful and engaging text that will appeal to those interested in public health and anthropology.

This book compares the policy approaches taken by China and India in dealing with HIV/AIDS, illuminating the challenges they face as they grapple with this intractable disease and identifying best practices for dealing with HIV/AIDS in the developing world and beyond.

The Public Health Service has estimated there are 1,100,000 intravenous drug users in the United States, with about 235,000 infected with HIV. Treatment of substance abusers has an extensive and varied history; no consensus has emerged as to which approach works best. The author has compiled information from a vast array of sources to provide this resource guide with the important issues involved in HIV infection and intravenous drug use. He presents sections on historical background, behavioral antecedents, virology, immunology, incidence, prevalence, HIV testing, treatment, counseling, confidentiality, methodological issues, and the latest scientific findings, based upon his clinical experience and synthesis of the research literature. Physicians, nurses, psychologists, social workers, health educators, and public health officials who are addressing issues related to HIV infection and intravenous drug use will find this handbook useful.

-Accessible introduction to the full spectrum of diseases and disasters for students of politics, human security studies and development studies -Case studies include Covid-19, Haiti Earthquake 2010, Hurricane Maria, Typhoon Haiyan, Second Congo War; Yemen Civil War; Tajikistan Civil War, AIDS in Africa, Malaria, SARS, and Ebola -Timely new textbook to address issues arising from the Covid-19 global pandemic

Is There a Link between the Nature of Agents That Trigger Mast Cells and the Induction of Immunoglobulin (IG)E Synthesis?.- Immunogenetic Aspects of IgE-Mediated Responses.- Structure and Function of the Low Affinity IgE Receptor.- Characterization of the Human IgE Fc-Fce RIa Interaction.- The Analysis of Mast Cell Function in Vivo Using Mast Cell-Deficient Mice.- The Immunogenetic Basis of Collagen Induced Arthritis in Mice: An Experimental Model for the Rational Design of Immunomodulatory Treatments of Rheumatoid Arthritis.- Suppression of Experimental Autoimmune Myasthenia Gravis by Epitope-Specific Neonatal Tolerance.- T Cell Reactivity to Self and Allogeneic MHC-Peptides.- Antiribosomal Antibodies in SLE, Infection, and Following Deliberate Immunization.- Cross-Reactions of Anti-Immunoglobulin Sera with Synthetic T-Cell Receptor ? Peptides: Mapping on a 3-Dimension Model.- Stress Proteins in Autoimmunity.- Polyclonal B Cell Activation and B Cell Cross-Reactivity During Autoantibody Production in Systemic Lupus Erythematosus.- Autoantibody Activity and V Gene Usage by B-Cell Malignancies.- Naturally Occurring Human Autoantibodies to Defend T-Cell Receptor and Light Chain Peptides.- Natural Autoantibodies.- Regulatory Autoantibody and Cellular Aging and Removal.- B-Cell Origin of Cold Agglutinins.- Initiation of Autoimmune Type 1 Diabetes and Molecular Cloning of a Gene Encoding for Islet Cell-Specific 37KD Autoantigen.- Mapping of the Polypeptide Chain Organization of the Main Extracellular Domain of the ?-Subunit in Membrane-Bound Acetylcholine Receptor by Anti-Peptide Antibodies Spanning the Entire Domain.

T-Cell/Macrophage Activation and HIV Infection.- 1. CD4+ and CD8+ T Lymphocyte Activation in HIV Infection: Implications for Immune Pathogenesis and Therapy.- 2. Markers of Immune Cell Activation and Disease Progression: Cell Activation in HIV Disease.- 3. The Role of the Cell Cycle in HIV-1 Infection.- 4. Molecular Basis of Cell Cycle Dependent HIV-1 Replication: Implications for Control of Virus Burden.- 5. Regulation of Macrophage Activation and HIV Replication.- 6. Investigations on Autologous T-Cells for Adoptive Immunotherapy of AIDS.- 7. Rational Problems Associated with the Development of Cellular Approaches in Controlling HIV Spread.- Apoptosis and Viropathogenesis of HIV Disease.- 8. The Role of Surface CD4 in HIV-Induced Apoptosis.- 9. Mechanism of Apoptosis in Peripheral Blood Mononuclear Cells of HIV-Infected Patients.- 10. Programmed Death of T Cells in the Course of HIV Infection.- 11. T Cell Apoptosis as a Consequence of Chronic Activation of the Immune System in HIV Infection.- 12. Apoptosis during HIV Infection: A Cytopathic Effect of HIV or an Important Host-Defense Mechanism against Viruses in General?.- Apoptosis and Immunopathogenesis of HIV Disease.- 13. From Cell Activation to Cell Depletion: The Programmed Cell Death Hypothesis of AIDS Pathogenesis.- 14. Immunosuppression by a Noncytolytic Virus Via T Cell Mediated Immunopathology: Implication for AIDS.- 15. Clonal Expansion of T Cells and HIV Genotypes in Microdissected Splenic White Pulps Indicates Viral Replication in Situ and Infiltration of HIV-Specific Cytotoxic T Lymphocytes.- 16. Autoimmunity, Apoptosis Defects, and Retroviruses.- 17. AIDS as Immune System Activation: Key Questions that Remain.- Mediators of T-Cell Activation/Apoptosis and Therapeutic Applications.- 18. Inhibition of T Lymphocyte Activation and Apoptotic Cell Death by Cyclosporin A and Tacrolimus (FK506): Its Relevance to Therapy of HIV Infection.- 19. Cyclophilin and Gag in HIV-1 Replication and Pathogenesis.- 20. Long-Term Follow-up of HIV Positive Asymptomatic Patients Having Received Cyclosporin A.- 21. Prospective Views of HIV Pathology: Clues for Therapeutic Strategies.

Written by a leading expert in the field, this book provides a clear and incisive analysis of the different perspectives of the global response to HIV/AIDS, and the role of the different global institutions involved. The text highlights HIV/AIDS as an exceptional global epidemic in terms of the severity of its impact as a humanitarian tragedy of unprecedented proportion, its multi-dimensional characteristics, and its continuous evolution over more than two decades. The careful analysis in this volume critically reviews key issues in the global response, including: HIV/AIDS as a development challenge North-South power relationships and tensions international and regional partnerships between donor governments and recipient countries governance of global institutions and impact on the capacity of developing countries to respond effectively to the epidemic prevention versus treatment as options in HIV/AIDS services how to make the money work in support of effective AIDS financing. Providing a comprehensive but easy to read and compact overview of history, trends and impacts of HIV/AIDS and the global efforts to respond effectively this book is essential reading for all students of international relations, health studies and international organizations.

Whether, with whom, and when to have children are among the most precious of our private decisions. Increasingly, however, the interest of others in these decisions raise difficult questions about the role of government and health professionals in influencing reproductive choice. Nowhere is this tension felt more keenly than in the context of HIV and AIDS. This book takes on the tough issues related to HIV and childbearing: Is there a moral right to have children? What are the limits of persuasion? Are there constitutional constraints on interference with reproduction? What are the precedents with restricting the childbearing behavior of women who use drugs? The book includes original work by doctors, lawyers, ethicists, and public health professionals. Also included are the experiences of HIV-infected women and their health care providers. Interviews were conducted over a two-year period with HIV-infected women and with health care providers from four cities to examine what issues of childbearing in the context of HIV mean to them. The book is divided into four sections on medical and public health issues, legal issues, ethical and social issues, and comments from the community. It concludes with recommendations for clinical practice and public policy. Public policy makers, health care providers, practitioners in bioethics, pediatrics, health law, and obstetrics/gynecology will find this book invaluable when dealing with issues related to HIV and childbearing.

How successful are HIV prevention programs? Which HIV prevention programs are most cost effective? Which programs are worth expanding and which should be abandoned altogether? This book addresses the quantitative evaluation of HIV prevention programs, assessing for the first time several different quantitative methods of evaluation. The authors of the book include behavioral scientists, biologists, economists, epidemiologists, health service researchers, operations researchers, policy makers, and statisticians. They present a wide variety of perspectives on the subject, including an overview of HIV prevention programs in developing countries, economic analyses that address questions of cost effectiveness and resource allocation, case studies such as Israel's ban on Ethiopian blood donors, and descriptions of new methodologies and problems.

Thanks to enormous funding for educational programs, the whole world ?knows? that HIV causes AIDS. But is what we know compatible with the facts? This book challenges the conventional wisdom on this issue. Collating and analyzing, for the first time, the results of more than two decades of HIV testing, it reveals that the common assumptions about HIV and AIDS are incompatible with the published data. Among the many topics explored are the failings of HIV testing, statistical evidence that HIV is neither sexually transmitted nor increasingly prevalent, and problems caused by the differing diagnostic criteria for AIDS around the world. But how could everyone have been so wrong for so long? This vital question, unaddressed in previous works questioning the HIV-AIDS connection, is central to this book. The author considers comparable missteps of modern science, and discusses how funding influences discovery in today's scientific circles.

The political impact of HIV/AIDS varies greatly and is difficult to map. States depend on how governments choose to manage the political implications of HIV and AIDS, both the implications stemming from the erosions of its own capacity, as well as those stemming from their changing relationship both nationally as well as internationally. Across the developing world, HIV/AIDS is slowly killing adults in their most productive years, hollowing out state-structures, deepening poverty, reversing achievements in education, lowering productivity, weakening intergenerational formation, and changing the composition of families. Clearly, in terms of its trajectory and impact, the epidemic raises profound questions that touch on the organization of all aspects of social, economic and political life. With the epidemic showing scant signs of slowing down anywhere in the developing world, this volume assesses how HIV/AIDS affects governance, and conversely how governance affects the course of the epidemic. This title employs a compelling analytical and polemic framework for mapping the multiple dynamic mechanisms of governance and HIV/AIDS.It brings together contributions from renowned international scholars from a variety of disciplines. It is an innovative text drawing on comprehensive as well as detailed perspectives on the roles of actors, institutions and structures. It offers an incisive study of a global plague which threatens existing social, economic and human interrelations. The specific dynamics and mechanisms for how HIV/AIDS impacts on actors, institutions or frameworks, as well as how their responses and changes affect the epidemic, require the careful judgment and analysis of the contributors. The authors offer their informed views on factors that have been conducive as well as constraining in actors to respond, which allows for a comprehensive picture of the 'politics of reform' as well as 'effective practices'.

Findings from the field of evolutionary biology are yielding dramatic insights for health scientists, especially those involved in the fight against infectious diseases. This book is the first in-depth presentation of these insights. In detailing why the pathogens that cause malaria, smallpox, tuberculosis, and AIDS have their special kinds of deadliness, the book shows how efforts to control virtually all diseases would benefit from a more thorough application of evolutionary principles. When viewed from a Darwinian perspective, a pathogen is not simply a disease-causing agent, it is a self-replicating organism driven by evolutionary pressures to pass on as many copies of itself as possible. In this context, so-called "cultural vectors"--those aspects of human behavior and the human environment that allow spread of disease from immobilized people--become more important than ever. Interventions to control diseases don't simply hinder their spread but can cause pathogens and the diseases they engender to evolve into more benign forms. In fact, the union of health science with evolutionary biology offers an entirely new dimension to policy making, as the possibility of determining the future course of many diseases becomes a reality. By presenting the first detailed explanation of an evolutionary perspective on infectious disease, the author has achieved a genuine milestone in the synthesis of health science, epidemiology, and evolutionary biology. Written in a clear, accessible style, it is intended for a wide readership among professionals in these fields and general readers interested in science and health.

Despite the growth of various forms of online discussion, their impact on American political life is only beginning to be examined systematically. In Politics Online Richard Davis provides a thorough analysis detailing the political attitudes, behavior, and demographic nature of the electronic discussion community contrasting that community with the general public.

Despite the growth of various forms of online discussion, their impact on American political life is only beginning to be examined systematically. In Politics Online Richard Davis provides a thorough analysis detailing the political attitudes, behavior, and demographic nature of the electronic discussion community contrasting that community with the general public.

Dermatologists are often the first medical professionals to see patients with HIV infection, as skin diseases are common in acquired immunodeficiency syndrome. This book aims to help dermatologists recognize the cutaneous manifestations of HIV infection and AIDS, so that diagnosis can be made quickly and therapy begun as soon as possible. The book covers the entire spectrum of HIV-associated cutaneous diseases, and emphasizes how they present in immunocompromised patients. A wide range of skin disorders are covered, including infections caused by bacterial, parasitic and fungal agents. The latest treatments are described, including Highly Active Antiretroviral Therapy (HAART). Each condition is discussed in detail, with information on clinical presentation, histopathological findings, morphology, and treatment - as well as possible side-effects. The text is accompanied by colour photos of the highest quality.

Historically, AIDS is just one of a series of dreaded diseases that have aroused both great fear and irrational actions. The previous diseases, including bubonic plague, syphilis, tuberculosis, leprosy and cancer, have evoked such a sense of dread that rational moves to halt the disease have become compromised.;This text examines the deep sense of fear that AIDS evokes, stigmatizing those who suffer from the disease, as well as their families and caregivers. Until AIDS can be seen for what it actually is - a life-threatening disease - policies providing for humane treatment will not evolve. The book also emphasizes that diseases are more than biological phenomena or individual catastrophes - they are profoundly social events. The ways in which diseases are spread and treated are strongly influenced by larger sociological considerations, and they may have the capacity to change social institutions or society itself. Rooting AIDS in the history of diseases, the first part of the book reviews the nature, history and responses of earlier dreaded diseases. The next section examines AIDS itself, proposed as the archetypal dreaded disease. Already creating a sense of panic, AIDS is also s

Evidence shows that nutritional supports can help maintain health in the HIV-infected patient by replacing lost nutrients, compensating for nutritional damage done by the retrovirus-induced immunodeficiency, and stimulating the remaining immune system and cells for better host defenses.

This new edition of Nutrition and AIDS is a timely look at what dietary materials, supplements, and foods may benefit or treat AIDS, as well as nutritional deficiencies that can accelerate progression to AIDS and death. It offers a variety of alternative dietary and herbal remedies, including some that have been tested in animals and humans to stimulate immune defense or compensate for changes induced by HIV infection. In addition, it surveys items that may accelerate nutritional depletion in AIDS patients, such as cocaine, alcohol, and tobacco use. It includes data from animal studies modeling AIDS and nutrition, studies not yet done in humans but applicable to them.

Including updated reviews on topics from the author's earlier publications on the subject, with a focus on how to use this nutritional information to treat or retard development of AIDS, Nutrition and AIDS brings to the forefront the most recent advances in understanding the nutritional deficiencies of AIDS and HIV-positive patients.

This book explores the normalization of HIV and AIDS, reflecting upon the intended and unintended consequences of the multifarious "AIDS industry."

The Normalization of the HIV and AIDS Epidemic in South Africa deals with the manner in which the HIV and AIDS epidemic has become such a well-known disease with such wide-ranging ramifications. With its focus on the "AIDS industry," this book examines issues such as the framing of the HIV and AIDS epidemic in a manner that greatly fostered notions of stigmatization and moralization. This book looks at the complexities of dealing with the epidemic in contemporary South Africa, examining the difficulties of addressing the social aspects of a disease in the context of increased focus on technological quick-fix solutions. De Wet explores these issues thoroughly, looking at the social determinants of the spread of the disease as well as the configuration and the nature of the responses to it, and their increasing marginalization as factors to address in an era of increased biomedicalization and concomitant normalization.

This book will intrigue scholars and students of public health, global health care, medical sociology, and African Studies.

Table of Contents

1. From Exceptionality to Ordinariness: How HIV and AIDS Lost its Sex Appeal 2. Dollars, Donors, and Drugs: South Africa in the Era of Global Health 3. "Thin Citizenship" of Community Health Workers 4. The Continued Relevance of HIV and AIDS Activism: "Help Prevent a Sequel" ... 5. The AIDS Industry: Entanglements, Ethics, and The Future of AIDS As We Know It

The latest in the crucial series documenting scientific discoveries at the forefront of HIV and AIDS research
This volume updates the most important and controversial issues facing physicians, nurses, microbiologists, pharmacists, and epidemiologists who deal directly with patients suffering from HIV and AIDS, focusing on specific areas in which important new advances have occurred in diagnosis, therapy, and prevention of infection and related complications.
Outlines new disease management strategies being tested in prospective clinical trials and observational studies
Combining elements of virology, epidemiology, immunology, oncology, endocrinology, neurology, psychiatry, and the behavioral sciences, AIDS Clinical Review 2000/2001
clarifies substantive advancements in vaccine development, realistically assessing potential efficacy and limitations
explores short-term antiretroviral therapy for dramatically reducing the rate of vertical transmission from mother to child
evaluates the efficacy of antiretroviral prophylaxis for workers who experience high-risk exposure to HIV-infected blood
discusses preservation of HIV specific immunity when antiretroviral therapy is initiated early in the course of acute infection
considers complex drug interactions that occur when drugs are used in combination
highlights cytokine and other immune-based therapies
suggests chronic hepatitis may ultimately be more fatal than HIV for coinfected patients
and more
Including results recently presented at scientific meetings but not yet published in peer-reviewed journals, AIDS Clinical Review 2000/2001 is essential reading for infectious disease specialists, epidemiologists, virologists, immunologists, pharmacologists, microbiologists, hematologists, hepatologists, oncologists, neurologists, medical students in these disciplines, and all medical professionals involved in both AIDS research and clinical practice.