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Blood Cell Biochemistry, v. 3 - Lymphocytes and Granulocytes (Hardcover, New)
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Blood Cell Biochemistry, v. 3 - Lymphocytes and Granulocytes (Hardcover, New)
Series: Blood Cell Biochemistry, 3
Expected to ship within 12 - 17 working days
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1 Biochemical, Immunological, and Molecular Markers of Hemopoietic
Precursor Cells.- 1. Introduction.- 2. Biochemical Markers.- 2.1.
Terminal Deoxynucleotide Transferase.- 2.2. Enzymes in Nucleotide
Metabolism.- 3. Immunological Markers.- 4. Molecular Markers.- 5.
Analysis of Human Hemopoietic Ontogenesis by Immunological and
Molecular Markers.- 6. New Opportunities for Immunological and
Molecular Markers: Minimal Residual Disease Detection and
Therapeutical Approaches.- 7. References.- 2 Cell Surface Markers
in Leukemia and Lymphoma.- 1. Introduction.- 2. B Cells.- 2.1.
Normal B-Cell Ontogeny.- 2.2. B-Cell Leukemias and Lymphomas.- 3. T
Cells.- 3.1. Normal T-Cell Ontogeny.- 3.2. T-Cell Leukemias and
Lymphomas.- 4. Myeloid Cells.- 4.1. Normal Myeloid Ontogeny.- 4.2.
Myeloid Leukemias.- 5. Summary.- 6. References.- 3 Cytoskeletal
Organization of Normal and Leukemic Lymphocytes and Lymphoblasts.-
1. Introduction.- 2. Microfilaments in Normal and Leukemic
Lymphocytes and Lymphoblasts.- 2.1. Actin and Actin-Associated
Proteins in Nonmuscle Cells.- 2.2. Actin Isoforms.- 2.3.
Organization of Actin in Normal Lymphocytes.- 2.4. Interactions
between Actin and Surface Antigens in Lymphocytes.- 2.5. Actin in
Leukemic Lymphocytes and Lymphoblasts.- 3. Intermediate-Size
Filaments in Normal and Leukemic Lymphocytes and Lymphoblasts.-
3.1. The Intermediate Filament System.- 3.2. Distribution of
Vimentin in Lymphocytes in Normal Conditions.- 3.3. Vimentin in
Neoplastic Lymphocytes and Lymphoblasts.- 3.4. Expression of
Cytokeratin in Lymphoid Tissues.- 4. Microtubules in Lymphoid
Cells.- 5. Organization of Spectrin in Lymphocytes.- 6.
Conclusions.- 7. References.- 4 Signaling Events in
T-Lymphocyte-Dependent B-Lymphocyte Activation.- 1. Introduction.-
2. B-Cell Antigen Receptor-Mediated Signaling.- 3. Molecular Bases
of T-Cell-Mediated B-Cell Signaling.- 4. Biological Evidence for
Ia-Mediated Signal Transduction.- 5. Biochemical Evidence for
Ia-Mediated Signal Transduction.- 6. Conclusions.- 7. References.-
5 IgE Receptors on Lymphocytes and IgE-Binding Factors.- 1.
Introduction.- 2. Historical Overview.- 3. Fc?RII on Lymphocytes.-
3.1. Fc?RII-Bearing Cells.- 3.2. Function of Fc?RII.- 3.3.
Molecular Properties of Fc?RII.- 3.4. Regulation of Fc?RII
Expression on Lymphocytes.- 4. IgE-Binding Factors.- 4.1. Rat.-
4.2. Murine.- 4.3. Human.- 5. Glycosylation-Regulating Factors: GEF
and GIF.- 5.1. Rat.- 5.2. Murine.- 6. Interleukin 4 and Gamma
Interferon.- 7. CD23 Antigen.- 8. Conclusion.- 9. References.- 6
Lymphocyte-Mediated Cytolysis: Role of Granule Mediators.- 1. Role
of Granules and Perform in Lymphocyte-Mediated Killing.- 1.1. The
Granule Exocytosis or Secretion Model for Cell Killing.- 1.2.
Cytoplasmic Granules and Perform as Mediators of Cytotoxicity.-
1.3. A Family of Serine Esterases Localized in Lymphocyte
Granules.- 1.4. Proteoglycans.- 1.5. Leukalexins and Cytokines
Related to Tumor Necrosis Factor and Lymphotoxin.- 2. Other
Candidate Mechanisms of Lymphocyte-Mediated Killing.- 3. Resistance
of Lymphocytes to Self-Mediated Killing.- 4. Conclusion.- 5.
References.- 7 CR1-Cytoskeleton Interactions in Neutrophils.- 1.
Introduction.- 2. Detergent Extraction of Cells.- 3.
Receptor-Cytoskeleton Interactions.- 4. The C3b Receptor (CR1).- 5.
References.- 8 The Flow of Granular Organelles in Leukocyte
Differentiation.- 1. Introduction.- 2. Biogenesis of Membrane-Bound
Organelles.- 2.1. Introduction.- 2.2. Endoplasmic Reticulum.- 2.3.
Golgi Complex.- 2.4. Lysosomes.- 2.5. Communication between
Compartments: Endosomes.- 2.6. Secretory Granules.- 3. Leukocyte
Granules are Major Determinants of Function.- 3.1. Neutrophils.-
3.2. Platelets.- 3.3. Cytotoxic Lymphocytes.- 4. Granules Interact
with the Plasma Membrane.- 4.1. Neutrophils.- 4.2. Platelets.- 5.
Pathology of Myeloid Granules and Plasma Membranes.- 5.1.
Nonneoplastic.- 5.2. Leukemic.- 6. Conclusion.- 7. References.- 9
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