Oncogene-Directed Therapies (Paperback, Softcover reprint of the original 1st ed. 2003)

Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer. The contributors explain how, why, and under what conditions certain proteins acquire the ability to transform eukaryotic cells, and detail the crucial biological consequences of this oncogenic transformation, particularly for cellular mitogenesis, survival, differentiation, migration, proteolysis, or angiogenic competence. Their articles thoroughly explicate the premises, principles, techniques, and approaches to oncogene targeting in various types of human cancer by using signal transduction inhibitors, immunological targeting methods, and antisense gene therapy.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Cancer Drug Discovery and Development
Release date:	July 2012
First published:	2003
Editors:	Janusz W. Rak
Dimensions:	254 x 178 x 26mm (L x W x T)
Format:	Paperback
Pages:	487
Edition:	Softcover reprint of the original 1st ed. 2003
ISBN-13:	978-1-4684-9738-0
Categories:	Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-4684-9738-3
Barcode:	9781468497380

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