Books > Medicine > Clinical & internal medicine > Haematology
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Clotting Disorders - Symptoms, Diagnosis & Management (Hardcover)
Loot Price: R3,613
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Clotting Disorders - Symptoms, Diagnosis & Management (Hardcover)
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Coagulopathy (also called clotting disorder and bleeding disorder)
is a condition in which the blood's ability to clot (coagulate) is
impaired. Acquired hemophilia is a rare disorder characterized by
spontaneous bleeding in a patient with no previous personal or
family hemorrhagic history. The first chapter explores the
challenges associated with this disease, its unfamiliarity often
causing a delay in diagnosis and therapeutic approaches. The second
chapter focuses on lower gastrointestinal bleeding (LGIB) in
children, describing the epidemiology, etiology and clinical
management. The third chapter reviews the pathogenesis, risk
factors and treatment strategies of coagulopathy in patients with
craniocerebral injury. The next article examines Vitamin B12 with
its four cobalamin vitamers, which often play a role in
coagulation. The next chapter starts with a description of the
methodology of viscoelastic hemostatic assay, followed by a review
of literature on the utilization of thrombelastography (TEG) or
rotational thromboelastometry (ROTEM). Finally, the role of TEG and
ROTEM to monitor or guide prophylaxis/treatment of thromboembolic
events and the limitations of using them to detect
hypercoagulability and identify patients with increased risks for
thromboembolic complications are discussed. The final chapter of
this book focuses on the use of fresh frozen plasma (FFP) in
patients who are not actively bleeding, critically questions these
assumptions in the context of pre-procedural administration of FFP,
and also examines why carrying out high quality trails in this area
has been so problematic.
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