Fc Mediated Activity of Antibodies - Structural and Functional Diversity (Hardcover, 1st ed. 2019)

This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Current Topics in Microbiology and Immunology, 423
Release date:	September 2019
First published:	2019
Editors:	Jeffrey V. Ravetch • Falk Nimmerjahn
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	150
Edition:	1st ed. 2019
ISBN-13:	978-3-03-031052-3
Categories:	Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General Promotions
LSN:	3-03-031052-3
Barcode:	9783030310523

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