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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Fc Mediated Activity of Antibodies - Structural and Functional Diversity (Hardcover, 1st ed. 2019)
Loot Price: R3,353
Discovery Miles 33 530
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Fc Mediated Activity of Antibodies - Structural and Functional Diversity (Hardcover, 1st ed. 2019)
Series: Current Topics in Microbiology and Immunology, 423
Expected to ship within 10 - 15 working days
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This volume explores several aspects of how antibodies mediate
their activity in vivo, ranging from cancer immunotherapy to
autoimmunity, infection, and vaccination. Divided into seven
chapters, it provides in-depth insights into how antibodies and
especially the antibody fragment crystallizable (Fc) domain
modulate immune responses and antibody activity. The book begins by
discussing evolutionary aspects of how the family of Fc receptors
that are the key molecules for antibody activity evolved. In turn,
it addresses the molecular and cellular pathways underlying IgG
activity in cancer immunotherapy, and focuses on how IgG
glycosylation regulates IgG and IgE activity in autoimmunity,
allergy and infection. In closing, it presents strategies for
developing novel antibody-based vaccination approaches. The book is
intended for a very broad readership, including graduate students,
postdocs and principal investigators with a basic grasp of
immunology.
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