Chagas disease causes severe socioeconomic impact and a high
medical cost in Latin America. WHO and the World Bank consider
Chagas disease as the fourth most transmittable disease to have a
major impact on public health in Latin America: 120 million persons
are potentially exposed, 16 to 18 million of whom are presently
infected, causing 45,000 to 50,000 deaths per year. It has been
calculated that approximately 2.4 million potential working years
are lost because of incapacity and mortality due to the disease,
for an annual cost estimated at 20 billion Euros. American
Trypanosomiasis provides a comprehensive overview of Chagas disease
and discusses the latest discoveries concerning the three elements
that compose the transmission chain of the disease: The host: human
and mammalian reservoirs The insect vectors: domestic and sylvatic
vectors The causative parasite: Trypanosoma cruzi
General
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