Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification (Paperback, Softcover reprint of the original 1st ed. 2016)

This thesis focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of "affinity guided covalent conjugation." This newly established methodology provides complementary resolution to protein labeling, imaging and trafficking. By systematically investigating the coordination interaction between protein and quantum dots using various engineered protein ligands, this thesis proposes a general rule for protein self-assembly on the surface of quantum dots and reports a revolutionized nanobelt protein in accordance with this rule. It is an extraordinary example of interdisciplinary research, providing answers to real-life biological problems from a chemistry perspective.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Springer Theses
Release date:	June 2018
First published:	2016
Authors:	Jianpeng Wang
Dimensions:	235 x 155 x 6mm (L x W x T)
Format:	Paperback
Pages:	96
Edition:	Softcover reprint of the original 1st ed. 2016
ISBN-13:	978-3-662-57134-7
Categories:	Books > Professional & Technical > Technology: general issues > Nanotechnology Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins Books > Professional & Technical > Biochemical engineering > Biotechnology > General
LSN:	3-662-57134-X
Barcode:	9783662571347

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