This volume provides a wide spectrum of multidisciplinary
approaches for studying RNA structure and dynamics, including
detailed accounts of experimental and computational procedures.
Chapters guide readers through cryo-electron microscopy,
crystallography, isothermal titration calorimetry, small angle
X-ray scattering, single-molecule Foerster Energy transfer, X-ray
free electron laser, atomic force microscopy, computational
simulation, and prediction. Written in the format of the highly
successful Methods in Molecular Biology series, each chapter
includes an introduction to the topic, lists necessary materials
and reagents, includes tips on troubleshooting and known pitfalls,
and step-by-step, readily reproducible protocols. Authoritative and
cutting-edge, RNA Structure and Dynamics aims to be a foundation
for future studies and to be a source of inspiration for new
investigations in the field.
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