This textbook was written for an audience of advanced
undergraduates and graduate students who want a deeper
understanding of the chemical reactions that take place in living
organisms. The authors assume readers have a background in organic
chemistry at the level of the typical two-semester college course.
Although enzymes are crucial to biological reactions, the authors'
focus always remains on the reactivity patterns of the substrate
molecules and on the organic, arrow-pushing details of the
individual reactions. All mechanisms have been updated in this
second edition, and several hundred references to recent literature
are given for those students who want more detail.
General
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