Any research that uses new organic chemicals, or ones that are
not commercially available, will at some time require the synthesis
of such compounds. Therefore, organic synthesis is important in
many areas of both applied and academic research, from chemistry to
biology, biochemistry, and materials science. The third edition of
a bestseller, Advanced Practical Organic Chemistry is a guide that
explains the basic techniques of organic chemistry, presenting the
necessary information for readers to carry out widely used modern
organic synthesis reactions.
This book is written for advanced undergraduate and graduate
students as well as industrial organic chemists, particularly those
involved in pharmaceutical, agrochemical, and other areas of fine
chemical research. It provides the novice or nonspecialist with the
often difficult-to-find information on reagent properties needed to
perform general techniques. With over 80 years combined experience
training and developing organic research chemists in industry and
academia, the authors offer sufficient guidance for researchers to
perform reactions under conditions that give the highest chance of
success, including the appropriate precautions to take and proper
experimental protocols. The text also covers the following
topics:
- Record keeping and equipment
- Solvent purification and reagent preparation
- Using gases and working with vacuum pumps
- Purification, including crystallization and distillation
- Small-scale and large-scale reactions
- Characterization, including NMR spectra, melting point and
boiling point, and microanalysis
- Efficient ways to find information in the chemical
literature
With fully updated text and all newly drawn figures, the third
edition provides a powerful tool for building the knowledge on the
most up-to-date techniques commonly used in organic synthesis.
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