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Inflammatory Diseases and Copper - The Metabolic and Therapeutic Roles of Copper and Other Essential Metalloelements in Humans (Hardcover, 1982 ed.)
Loot Price: R5,806
Discovery Miles 58 060
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Inflammatory Diseases and Copper - The Metabolic and Therapeutic Roles of Copper and Other Essential Metalloelements in Humans (Hardcover, 1982 ed.)
Series: Experimental Biology and Medicine, 2
Expected to ship within 10 - 15 working days
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Total price: R5,826
Discovery Miles: 58 260
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In 1928, it was discovered that copper was essential for normal
human metabolism. A decade later, in 1938, it was observed that
patients with rheu matoid arthritis exhibited a higher than normal
serum copper concentration that returned to normal with remission
of this disease. Thirteen years later, it was found that copper
complexes were effective in treating arthritic dis eases. The first
report that copper complexes had antiinflammatory activity in an
animal model of inflammation appeared twenty-two years after the
dis covery of essentiality. In 1976, it was suggested that the
active forms of the antiarthritic drugs are their copper complexes
formed in vivo. This sugges tion has been confirmed and extended in
the interim in over 200 recent publications. Individual biomedical
scientists from many countries who have published in these areas
recently saw a need for a meeting to exchange current re supporting
new hypotheses. We search results and discuss the evidence met on
the University of Arkansas Medical Sciences campus in Little Rock,
Arkansas, August 10-13, 1981. Participants came from Australia,
England, France, Germany, Israel, Italy, The Netherlands, Norway,
Poland, Scotland, Sweden, Switzerland, Wales, Zimbabwe, and over
twenty of the United States."
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