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The Story of Taxol - Nature and Politics in the Pursuit of an Anti-Cancer Drug (Paperback, Revised)
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The Story of Taxol - Nature and Politics in the Pursuit of an Anti-Cancer Drug (Paperback, Revised)
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Taxol is arguably the most celebrated, talked about, and
controversial natural product in recent years. Celebrated because
of its efficacy as an anticancer drug and because its discovery has
provided powerful support for policies concerned with biodiversity.
Talked about because in the early 1990s the American public was
bombarded with news reports about the molecule and its host, the
slow-growing Pacific yew tree. Controversial because the drug and
the yew tree became embroiled in several sensitive political issues
with broad public policy implications. Taxol has revolutionized the
treatment options for patients with advanced forms of breast and
ovarian cancers and some types of leukemia; it shows promise for
treating AIDS-related Kaposi's sarcoma. It is the best-selling
anticancer drug ever, with world sales of $1.2 billion in 1998 and
expected to grow. Goodman and Walsh's careful study of how taxol
was discovered, researched, and brought to market documents the
complexities and conflicting interests in the ongoing process to
find effective treatments. From a broader perspective, The Story of
Taxol uses the discovery and development of taxol as a paradigm to
address current issues in the history and sociology of science and
medicine. Jordan Goodman is a Senior Lecturer in History at the
Manchester School of Management, University of Manchester Institute
of Science & Technology. He has written on subjects as varied
as the history of medicine and economic history for journal
articles and in edited volumes. Goodman's previous books include
Tobacco in History (Routledge, 1994) and Consuming Habits: Drugs in
History and Anthropology (Routledge, 1995). Vivien Walsh is Reader
in Technology Management at the Manchester School of Management,
University of Manchester Institute of Science & Technology. She
has been researching the pharmaceutical and chemical industry for
years and is currently working on globalization of innovative
activity in the face of technological and organizational changes in
the chemical, pharmaceutical, and agro-food industries. Walsh has
been a consultant to the European Commission and to the
Organisation for Economic Cooperation and Development.
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