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An Introduction to Epidemiology for Health Professionals (Hardcover, 2010)
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An Introduction to Epidemiology for Health Professionals (Hardcover, 2010)
Series: Springer Series on Epidemiology and Public Health, 1
Expected to ship within 10 - 15 working days
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Therearemanygoodepidemiologytextbooksonthemarket,butmostoftheseare
addressedtostudentsofpublichealthorpeoplewhodoclinicalresearchwithe-
demiologicmethods.
Thereisaneedforashortintroductiononhowepidemiologic
methodsareusedinpublichealth,geneticandclinicalepidemiology,becausehealth
professionalsneedtoknowbasicepidemiologicmethodscoveringetiologicaswell
asprognosticfactorsofdiseases.
Theyneedtoknowmoreaboutmethodologythan
introductorytextsonpublichealthhavetooffer.
Insomehealthfaculties,epidemiologyisnotevenpartoftheteachingcurri-
lum. Webelievethistobeaseriousmistake.
Medicalstudentsarestudentsofall aspectsofdiseasesandhealth.
Withoutknowingsomethingaboutepidemiologythe
cliniciansandotherhealthprofessionalscannotreadagrowingpartofthesci-
ti
cliteratureinanyreasonablycriticalwayandcannotnavigateintheworldof
"evidence-basedmedicineandevidence-basedprevention.
"Withoutskillsine-
demiologicmethodologytheyareinthehandsofexpertsthatmaynotonlyhavean
interestinhealth. Some health professionals may believe that only
common sense is needed to
conductepidemiologicalstudies,butthescienti
cliteratureandthepublicdebate
onhealthissuesindicatethatcommonsenseisofteninshortsupplyandmaynot
thrivewithoutsomeformaltraining. Epidemiologic methods play a key
role in identifying environmental, social, and genetic determinants
of diseases. Clinical epidemiology addresses the tr-
sitionfromdiseasetohealthortowardmortalityorsocialormedicalhandicaps.
Publichealthepidemiologyaddressesthetransitionfrombeinghealthytobeingnot
healthy.
Descriptiveepidemiologyprovidesthediseasepatternthatisneededtolook
athealthinabroadperspectiveandtosettheprioritiesright.
Epidemiologyisabasic
scienceofmedicinewhichaddresseskeyquestionssuchas"Whobecomesill?"and
"Whatareimportantprognosticfactors?"Answerstosuchquestionsprovidethe
basisforbetterpreventionandtreatmentofdiseases. Many people
contributed to the writing of this book: medical students in
Denmark,studentsofepidemiologyattheIEAEEPEsummercourseinFlorence,
Italy,andstudentsofpublichealthinLosAngeles.
Withouttechnicalassistance v vi Preface
fromGitteNielsen,JenadeShelley,NinaHoheandPamMasangkaythebookwould
neverhavematerialized. LosAngeles,California JornOlsen
Odense,Denmark KaareChristensen IowaCity,Iowa JeffMurray
Stockholm,Sweden AndersEkbom Contents Part I Descriptive
Epidemiology 1 Measures of Disease Occurrence ...3
IncidenceandPrevalence ...4 Incidence...6
RatesandDynamicPopulations ...7 CalculatingObservationTime...9
Prevalence,Incidence,Duration ...10 MortalityandLifeExpectancy
...11 LifeExpectancy ...12 References...13 2 Estimates of
Associations ...15 3 Age Standardization...19 4 Causes of Diseases
...23 References...28 5 Descriptive Epidemiology in Public
Health...29 GraphicalModelsofCausalLinks ...33 References...35 6
Descriptive Epidemiology in Genetic Epidemiology...37
OccurrenceDatainGeneticEpidemiology ...37
ClusteringofTraitsandDiseasesinFamilies ...38
TheOccurrenceofGeneticDiseases ...40 References...41 7 Descriptive
Epidemiology in Clinical Epidemiology...43
SuddenInfantDeathSyndrome(SIDS)...44
CytologicalScreeningforCervixCancer ...45
ChangesinTreatmentofJuvenileDiabetes ...46 References...47 vii viii
Contents Part II Analytical Epidemiology 8 Design Options...51
CommonDesignsUsedtoEstimateAssociations...51 EcologicalStudy ...52
Case-ControlStudy...54 CohortStudy ...5 5 ExperimentalStudy ...56
Reference ...57 9 Follow-Up Studies ...59
TheNon-experimentalFollow-Up(Cohort)Study ...59
StudyingRiskasaFunctionofBMI ...60 LongitudinalExposureData...62
DifferentTypesofCohortorFollow-UpStudies...63 10 Case-Control
Studies...67 Case-CohortSampling ...69
DensitySamplingofControls...69 Case-Non-caseStudy...71
PatientControls ...72 SecondaryIdenti cationoftheSourcePopulation
...74 Case-ControlStudiesUsingPrevalentCases...74
WhentoDoaCase-ControlStudy? ...77 References...78 11 The
Cross-Sectional Study...79 12 The Randomized Controlled Trial (RCT)
...81 Reference ...
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