In this second edition of "Post-Genomic Cardiology, " developing
and new technologies such as translational genomics, next
generation sequencing (NGS), bioinformatics, and systems biology in
molecular cardiology are assessed in light of their therapeutic
potential. As new methods of mutation screening emerge, both for
the genome and for the epigenome, comprehensive understanding of
the many mutations that underlie cardiovascular diseases and
adverse drug reactions is within our reach.
This book, written by respected cardiologist Jose Marin-Garcia,
features discussion on the Hap-Map: the largest international
effort to date aiming to define the differences between our
individual genomes. This unique reference further reviews and
investigates genome sequences from our evolutionary relatives that
could help us decipher the signals of genes, and offers a
comprehensive and critical evaluation of regulatory elements from
the complicated network of the background DNA.
Offers updated discussion of cutting-edge molecular techniques
including new genomic sequencing / NGS / Hap-Map / bioinformatics /
systems biology approachesAnalyzes mitochondria dynamics and their
role in cardiac dysfunction, up-to-date analysis of
cardio-protection, and cardio-metabolic syndromePresents recent
translational studies, gene therapy, transplantation of stem cells,
and pharmacological treatments in CVDs"
General
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