Epi-Informatics: Discovery and Development of Small Molecule
Epigenetic Drugs and Probes features multidisciplinary strategies
with strong computational approaches that have led to the
successful discovery and/or optimization of compounds that act as
modulators of epigenetic targets. This book is intended for all
those using or wanting to learn more about computational
methodologies in epigenetic drug discovery, including molecular
modelers, informaticians, pharmaceutical scientists, and medicinal
chemists. With a better understanding of different molecular
modeling and cheminformatic approaches, readers can incorporate
these techniques into their own drug discovery projects that may
involve chemical synthesis and medium- or high-throughput
screening. In addition, this book highlights the significance of
epigenetic targets to the public health for molecular modelers and
chemoinformatians. The goal of this reference is to stimulate
ongoing multidisciplinary research and to further improve current
computational methodologies and workflows in order to accelerate
the discovery and development of epi-drugs and epi-probes.
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