VEGF and Cancer is a comprehensive and up to date review of
current knowledge on the role of vascular endothelial growth factor
(VEGF) in cancer.
Key Features:
-Discussion of VEGF as potent angiogenic factor and its role in
tumor angiogenesis,
-Review of the biology, molecular properties and regulation of
VEGF,
-Discussion of the role of VEGF in a range of different tumor
types, both solid tumors and haematological cancers,
-Review of the therapeutic potential of different approaches to
block VEGF,
-Review of recent evidence that in addition to its role as an
endothelial cell mitogen, VEGF may also be an autocrine growth
factor for tumor cells, regulating survival and invasion.
This book is aimed at scientists new to angiogenesis and VEGF
biology and provides new information for established researchers
and scientists. It will also be a useful text for clinicians
interested in anti-angiogenic therapy for treatment of human
cancers.
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