This volume emphasizes the intracellular consequences of DNA
damage, describing procedures for analysis of checkpoint responses,
DNA repair in vivo, replication fork encounter of DNA damage, as
well as biological methods for analysis of mutation production and
chromosome rearrangements. It also describes molecular methods for
analysis of a number of genome maintenance activities including DNA
ligases, helicases, and single-strand binding proteins.
*Part B of a 2-part series
*Addresses DNA maintenance enzymes
*Discusses damage signaling
*Presents "In vivo" analysis of DNA repair
*Covers mutation and chromosome rearrangements
General
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