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Target Identification and Validation in Drug Discovery - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2013)
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Target Identification and Validation in Drug Discovery - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2013)
Series: Methods in Molecular Biology, 986
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The major reason for the elevated costs of drug development in the
pharmaceutical industry is the high attrition rate. In Target
Identification and Validation in Drug Discovery: Methods and
Protocols, expert researchers in the field detail many of the
methods which are now commonly used to identify and validate new
target. These include methods and approaches covering biochemical,
cell based, in vivo models and translational methods. Chapters also
include selected case reports that demonstrate the integration of
these technologies to real life experiences and to demonstrate the
multiple use of more than one technology to increase knowledge on a
specific target. These Written in the highly successful Methods in
Molecular Biology (TM) series format, the chapters include the kind
of detailed description and implementation advice that is crucial
for getting optimal results in the laboratory. Thorough and
intuitive, Target Identification and Validation in Drug Discovery:
Methods and Protocols contains a comprehensive list of essential
methods and clear protocols to follow.
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