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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Genetic Approaches to Coronary Heart Disease and Hypertension (Paperback, Softcover reprint of the original 1st ed. 1991)
Loot Price: R2,846
Discovery Miles 28 460
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Genetic Approaches to Coronary Heart Disease and Hypertension (Paperback, Softcover reprint of the original 1st ed. 1991)
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Cardiovascular diseases are the principal cause of mortality in
many developed countries and are increasing in importance in
developing countries where communicable diseases are being brought
under control. It is estimated that coronary heart disease (CRD)
and cerebrovascular diseases are responsible for between 40-50% of
all deaths. Righ blood pressure is common in all industrialized
societies and contributes importantly to CRD. It is well known that
genetic factors play an important role in the etiology and
pathogenes es of cardiovascular diseases and contribute to an
individual's susceptibility or resistance to the disease. The
application of modern genetic techniques has resulted in the
identification of polymorphie markers that are involved in the
normal regulation and function of the cardiovascular system. Many
of these may contribute to the individual differences in the risk
for CRD and hypertension. It is now known that several risk factors
or protective factors with respect to cardiovascular diseases are
strongly influenced by genes, and it is now possible to identify
individual genes contributing to cardiovascular risk. A large bank
of genetic knowledge relevant to CRD and hypertension has become
available during the past years. As a result, it is now believed
that CRD, for example, could be a good model for a feasibility
study to determine a way by which preventive measures can be
applied.
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