This topical, handy volume is the perfect guide for physicians or
scientists not specializing in the field, but wishing to understand
exciting recent developments in cellular and molecular biology
relevant to oncogene research. The terminology used in discussing
oncogenes and their products is straightforwardly defined, and the
concepts crucial to an understanding of oncogene research are
clearly presented. Key topics are explored, including assay
techniques used in molecular biology; methods for assessing
behavior of normal genes and oncogenes; DNA and RNA tumor viruses;
viruses inducing immunodeficiency; cellular proto-oncogenes and
their relation to retroviral oncogenes; and possible roles of gene
amplification and mutation, chromosomal translocation, and cellular
growth factors in human cancer. An up-to-date survey of research on
the major oncogenes and a discussion of the possibilities for
future diagnostic and therapeutic applications of oncogene research
are provided. The presentation is enhanced through many original
illustrations, an appendix on oncogenes and related genes, and an
up-to-date bibliography.
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