Fifty patients of Rheumatoid arthritis were studied; 88% were
females. Rheumatoid factor was positive in 90%. Raised ESR and CRP
were markers of ongoing inflammation. The maximum number of
patients (98%) presented with articular symptoms; 14% of had
associated extra-articular symptoms; 2% presented only with
extra-articular manifestations.The most common joints to be
involved were the small joints of the hand, followed by the wrist,
elbow, toes, hip and knee joints. The disease related complications
seen commonly were various joint deformities and osteoporosis.
Spine involvement in the form of atlanto-axial dislocation was seen
in 2%.Extra-articular complications were episcleritis and
vasculitis syndrome, dryness of eyes and mouth, and rheumatoid
nodules. Postpartum flare of symptoms was seen in one patient. Drug
related complications were uncommon (22%); most of which were minor
side effects. Antirheumatic drugs especially DMARDs like
methotrexate are very much safe and have high acceptability among
the patients. Regular monitoring of patients is required. DAS 28
score is very helpful in assessing the patient response on
treatment with DMARDs.
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