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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Mechanisms of Cancer Metastasis - Potential Therapeutic Implications (Paperback, Softcover Repri)
Loot Price: R5,806
Discovery Miles 58 060
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Mechanisms of Cancer Metastasis - Potential Therapeutic Implications (Paperback, Softcover Repri)
Series: Developments in Oncology, 40
Expected to ship within 10 - 15 working days
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The past twenty years have witnessed significant advances in the
treatment of cancer by surgery and radiation therapy. Gains with
cytotoxic chemotherapy have been much more modest. Of the
approximately 900,000 newly diagnosed cases of cancer each year,
50010 result in death of the patient. The primary cause of these
deaths is metastasis. Although the term metastasis was first coined
by Recamier in 1829, only in the past ten years have there been
intensive scientific investigations into the mechanisms by which
tumor cells metastasize. What has emerged is a complex process of
host-tumor cell interactions which has been termed the metastatic
cascade. Due to the complexity of the metastatic process, the study
of metastasis is multifaceted and involves elements of such areas
as differentiation, en zymology, genetics, hematology, immunology,
membrane biochemistry and molecular biology. The major objectives
of this book were to present the most recent advances in our
understanding of how tumor cells metastasize to secondary sites by
the leading experts in the biology of tumor invasion and
metastasis. We hope that this book will lead to new concepts for
the treatment of subclinical metastatic cancer. The chapters in
this book address both the basic science of metastasis and
potential clinical therapies directed toward interruption of the
metastatic cascade or toward eradication of subclinical metastases.
Many relevant topics have been omitted due to space considerations
and thus the topics included reflect the prej udices of the
editors."
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